New method for closing surgical incisions after cesarean sections to prevent complications

Surgical Incision Closure Method to Prevent Niche Formation After Cesarean Section- Randomized Controlled Trial

Not applicable Interventional Hadassah Medical Organization · NCT04766073

This study is testing a new way to close surgical cuts after cesarean sections to see if it can help prevent complications like irregular bleeding and pelvic pain for women having their first cesarean delivery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment183 (estimated)
Ages17 Years to 50 Years
SexFemale
SponsorHadassah Medical Organization Academic / other
Locations1 site (Jerusalem)
Trial IDNCT04766073 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates a novel incision closure technique aimed at preventing the formation of niches after cesarean sections. A niche is a complication characterized by a defect in the uterine wall that can lead to various symptoms such as irregular bleeding and pelvic pain. The study will involve women undergoing their first cesarean delivery, who will be randomly assigned to receive either the new closure method or standard care. The primary goal is to assess whether this unique suture technique can effectively reduce the incidence of niche formation compared to traditional methods.

Who should consider this trial

Good fit: Ideal candidates for this study are women who are undergoing their first cesarean delivery and are willing to consent to participate.

Not a fit: Patients who are having a repeat cesarean section or those requiring urgent/emergent cesarean deliveries may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce complications associated with cesarean sections, improving quality of life for affected women.

How similar studies have performed: While previous studies have explored various surgical techniques for cesarean sections, this specific approach to preventing niche formation is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women at first cesarean delivery
* Women who consent to the study

Exclusion Criteria:

* Women who are having a repeat caesarean section
* Refusal to participate in the study
* Urgent or emergent cesarean delivery

Where this trial is running

Jerusalem

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cesarean Section ComplicationsUterine Bleeding
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.