Clinical trial Recruiting at 1 site Observational Ages 12 to 100

New diagnostic strategy for respiratory infections in fever clinics

Official title: Promotion and Application of a New Three-level Etiological Diagnosis Strategy for Fever Clinics in Respiratory Infectious Diseases

Run by Huashan Hospital · NCT05965128 · Data updated 2026-11-12

This study is testing a new way to quickly diagnose respiratory infections in patients with fever and cough to help doctors provide better care.

More Infectious Diseases trials

Quick facts

Study typeObservational
Ages12 Years to 100 Years
SexAll
Enrollment1255 (estimated)
SponsorHuashan Hospital
Academic / other
Locations12 sites (Lanzhou, Gansu and 11 other locations)
StatusRecruiting
StartedDecember 1, 2022
Main results expectedDecember 2023
Study endsDecember 2027
Registry record updatedJuly 28, 2023
Trial IDNCT05965128 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-70 who have acute respiratory symptoms and present with pneumonia or influenza-like illness.

Probably not a fit

Patients with structural disorders preventing sample collection or those unable to cooperate due to psychological issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project evaluates the effectiveness of a three-level pathogen diagnostic system in fever clinics to enhance the diagnosis of respiratory infectious diseases. It involves monitoring changes in respiratory pathogens and aims to provide real-time alerts for acute respiratory infections in Shanghai. Patients presenting with pneumonia or influenza-like symptoms will be assessed using step-by-step detection methods to optimize clinical resource allocation and improve patient outcomes.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the speed and accuracy of diagnosing respiratory infections, leading to better patient management.

How similar studies have gone: While similar diagnostic strategies have been explored, this specific three-level approach is novel and has not been widely tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Acute onset within one week;
2. 18-70 years old;
3. Present with pneumonia (present with pulmonary signs or radiological changes) or influenza-like illness (including the following symptoms: sudden onset of fever (\>38 ℃),plus cough and/or other respiratory symptoms such as shortness of breath plus one or more systemic symptoms (fatigue, headache ect.))

Exclusion Criteria:

1. Unable to collect nasal/nasopharyngeal swab/wash/aspirate due to structural disorder or mental problem.
2. Patients with psycological problem or unconsciousness who cannot tell the disease history and cooperate with medical examinations;

Where it's running

  • Fudan University Affiliated Huashan Hospital
    Shanghai, Shanghai Municipality, China
    Recruiting
  • Gansu Provincial People's Hospital
    Lanzhou, Gansu, China
    Not yet recruiting
  • Heilongjiang Provincial Hospital
    Harbin, Heilongjinag, China
    Not yet recruiting
  • People's Hospital of Inner Mongolia Autonomous Region
    Hohhot, Inner Mongolia, China
    Not yet recruiting
  • The First Affiliated Hospital of Suzhou University
    Suzhou, Jiangsu, China
    Not yet recruiting
  • Affiliated Hospital of Xuzhou Medical University
    Xuzhou, Jiangsu, China
    Not yet recruiting
Show 6 more locations
  • Shenyang Sixth People's Hospital
    Shenyang, Liaoning, China
    Not yet recruiting
  • Shandong University Qilu Hospital
    Jinan, Shandong, China
    Not yet recruiting
  • Jining Public Health Center
    Jining, Shandong, China
    Not yet recruiting
  • The First Hospital of Shanxi Medical University
    Taiyuan, Shanxi, China
    Not yet recruiting
  • The First People's Hospital of Yunnan Province
    Kunming, Yunnan, China
    Not yet recruiting
  • Ruian City People's Hospital
    Rui’an, Zhejiang, China
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.