New diagnostic strategy for respiratory infections in fever clinics
Official title: Promotion and Application of a New Three-level Etiological Diagnosis Strategy for Fever Clinics in Respiratory Infectious Diseases
Run by Huashan Hospital · NCT05965128 · Data updated 2026-11-12
This study is testing a new way to quickly diagnose respiratory infections in patients with fever and cough to help doctors provide better care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 12 Years to 100 Years |
| Sex | All |
| Enrollment | 1255 (estimated) |
| Sponsor | Huashan Hospital Academic / other |
| Locations | 12 sites (Lanzhou, Gansu and 11 other locations) |
| Status | Recruiting |
| Started | December 1, 2022 |
| Main results expected | December 2023 |
| Study ends | December 2027 |
| Registry record updated | July 28, 2023 |
| Trial ID | NCT05965128 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-70 who have acute respiratory symptoms and present with pneumonia or influenza-like illness.
✕Probably not a fit
Patients with structural disorders preventing sample collection or those unable to cooperate due to psychological issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project evaluates the effectiveness of a three-level pathogen diagnostic system in fever clinics to enhance the diagnosis of respiratory infectious diseases. It involves monitoring changes in respiratory pathogens and aims to provide real-time alerts for acute respiratory infections in Shanghai. Patients presenting with pneumonia or influenza-like symptoms will be assessed using step-by-step detection methods to optimize clinical resource allocation and improve patient outcomes.
Why it matters
Potential benefit: If successful, this approach could significantly enhance the speed and accuracy of diagnosing respiratory infections, leading to better patient management.
How similar studies have gone: While similar diagnostic strategies have been explored, this specific three-level approach is novel and has not been widely tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Acute onset within one week; 2. 18-70 years old; 3. Present with pneumonia (present with pulmonary signs or radiological changes) or influenza-like illness (including the following symptoms: sudden onset of fever (\>38 ℃),plus cough and/or other respiratory symptoms such as shortness of breath plus one or more systemic symptoms (fatigue, headache ect.)) Exclusion Criteria: 1. Unable to collect nasal/nasopharyngeal swab/wash/aspirate due to structural disorder or mental problem. 2. Patients with psycological problem or unconsciousness who cannot tell the disease history and cooperate with medical examinations;
Where it's running
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Fudan University Affiliated Huashan Hospital
Shanghai, Shanghai Municipality, China Recruiting -
Gansu Provincial People's Hospital
Lanzhou, Gansu, China Not yet recruiting -
Heilongjiang Provincial Hospital
Harbin, Heilongjinag, China Not yet recruiting -
People's Hospital of Inner Mongolia Autonomous Region
Hohhot, Inner Mongolia, China Not yet recruiting -
The First Affiliated Hospital of Suzhou University
Suzhou, Jiangsu, China Not yet recruiting -
Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China Not yet recruiting
Show 6 more locations
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Shenyang Sixth People's Hospital
Shenyang, Liaoning, China Not yet recruiting -
Shandong University Qilu Hospital
Jinan, Shandong, China Not yet recruiting -
Jining Public Health Center
Jining, Shandong, China Not yet recruiting -
The First Hospital of Shanxi Medical University
Taiyuan, Shanxi, China Not yet recruiting -
The First People's Hospital of Yunnan Province
Kunming, Yunnan, China Not yet recruiting -
Ruian City People's Hospital
Rui’an, Zhejiang, China Not yet recruiting
Study contacts
- Study coordinator: Wenhong Zhang, M.D.
- Email: zhangwenhong@fudan.edu.cn
- Phone: 13801844344
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.