New auto-adjusting PAP algorithm for obstructive sleep apnea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This blind, randomized crossover (or single-arm in the early phase) home-based study compares a novel auto-adjusting PAP algorithm with an established control algorithm in adults with obstructive sleep apnea who are established PAP users. Phase 1 is designed to confirm the algorithm functions as intended and allow minor software adjustments, while Phase 2 enrolls a broader participant group to collect objective device data and subjective user feedback. Participants will primarily use the devices at home and may be asked to wear a wearable during day and night for the study duration. Those who prefer the investigational algorithm after the main phases may opt into an optional extended use period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants willing to give written informed consent.
* Participants who can read and comprehend English.
* Participants who ≥ 18 years of age
* Participants who have been using a ResMed AirSense 10 or 11 device.
* Participants currently using AutoSet (APAP) mode.
* Participants being established on PAP therapy for the treatment of OSA for approximately \>3 months.
* Participants who can participate in the study for up to 8 weeks.

Exclusion Criteria:

* Participants using Bilevel flow generators.
* Participants using CPAP, AutoSet for Her
* Participants who are or may be pregnant.
* Participants with a preexisting lung disease/ condition that would predispose them to pneumothorax (for example: COPD, lung cancer; fibrosis of the lungs; recent (\< 2years) case of pneumonia or lung infection; lung injury.
* Participants believed to be unsuitable for inclusion by the researcher.
* Participants who are currently enrolled in other medical clinical studies

Where it's running

• ResMed Ltd
  Bella Vista, New South Wales, Australia Recruiting

Study contacts

• Study coordinator: Sumudu Herath
• Email: sumudu.herath@resmed.com.au
• Phone: +61 288841722

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Multimodal Deep Learning to Predict Sleep Apnea Severity from SpO2 and Ballistocardiography

  Researchers are testing a smart-mattress-based method that uses SpO2 and ballistocardiography data to predict sleep apnea severity in adults undergoing overnight sleep study.

  Recruiting Fu Jen Catholic University · New Taipei City, New Taipei City · NCT07923825

• Nightly wearable monitoring with at-home submental electrical stimulation for sleep apnea

  This pilot test checks whether wearing a ring sensor at night and doing a 4-week at-home submental electrical stimulation is feasible for adults with obstructive sleep apnea and looks at changes in sleep metrics.

  Recruiting E-DA Hospital · Kaohsiung City · NCT07921329

• Functional capacity and muscle function in adults with obstructive sleep apnea

  This study tests how obstructive sleep apnea affects respiratory and peripheral muscle strength, endurance, and upper‑extremity function compared with healthy adults.

  Recruiting Karabuk University · Karabük · NCT07913139

• Transcutaneous Electrical Stimulation for Obstructive Sleep Apnea

  This study tests whether applying gentle electrical stimulation to the throat muscles at night can reduce sleep apnea severity in adults with obstructive sleep apnea.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07891702

• Physical activity habits and sleep/ breathing in obstructive sleep apnea

  This study tests whether daily physical activity habits affect sleep quality and breathing measurements in people with obstructive sleep apnea who are on CPAP therapy.

  Recruiting Medipol University · Istanbul, Göztepe · NCT07889154

• CES-EES score and a wearable ring for diagnosing obstructive sleep apnea

  This study tests whether the CES-EES clinical score and the Belun Ring wearable can accurately diagnose obstructive sleep apnea without in-lab polysomnography in adults referred for suspected OSA.

  Recruiting University of Malaya · Pantai Valley, Kuala Lumpur · NCT07785999

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.