Neuropsychological and brain imaging evaluation in patients with brain damage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study involves two groups: patients with specific brain injuries or cognitive disorders and healthy control subjects. It aims to assess neuropsychological deficits and utilize advanced brain imaging techniques, such as anatomical and functional imaging, to understand the brain mechanisms behind these deficits. The interventions include neuropsychological testing, brain imaging, and galvanic vestibular stimulation. The goal is to provide insights into how brain damage affects cognitive functions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 17 years
* French language
* Effective contraception for women during the study
* Informed consent
* No alcohol intake the day before the exam
* For patients only, focal cerebral lesion (stroke, malformation, tumor, inflammatory, infectious, traumatic), neonatal pathology, developmental or degenerative disease with cognitive deficit

Exclusion Criteria:

* For healthy volunteers: previous neurological history (except non complicated migraine or epilepsy), previous psychiatric history (except depression with good evolution or anxiety), or severe cranial traumatism
* For patients: vigilance disorders, severe depression or anxiety.
* For both: psychotropic medication other than a hypnotic or an anxiolytic at low doses without dose modification for at least one month, severe visual or auditory impairment, patient without judicial or administrative liberty, measure of legal protection or no capable to express their consent, pregnancy or breastfeeding, contraindication for MRI or GVS if applicable, participation in another trial or former involvement in another trial within one month.

Where it's running

• Caen University Hospital
  Caen, France Recruiting

Study contacts

• Principal investigator: Olivier MARTINAUD, MD, PhD — Caen University Hospital, Normandie UNIV, UNICAEN, PSL Research University, EPHE, Inserm, U1077, CHU de Caen, Neuropsychologie et Imagerie de la Mémoire Humaine, 14000 Caen, France
• Study coordinator: Olivier MARTINAUD, MD, PhD
• Email: martinaud-o@chu-caen.fr
• Phone: 2 31 06 46 17

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• ICF-based interdisciplinary case management for adults with intellectual disability

  This study tests whether an ICF-based interdisciplinary case management approach can improve functioning, participation, and quality of life for adults with mild to moderate intellectual disability receiving community rehabilitation services.

  Recruiting The Hong Kong Polytechnic University · Hong Kong · NCT07813806

• Smart Inhaler Use at Home for Adolescents with IDD and Asthma

  This study tests whether daily use of active smart inhalers at home helps adolescents with intellectual disabilities manage asthma better.

  Recruiting Children's Hospital Los Angeles · Los Angeles, California · NCT07746921

• Best Care for Acute Stroke in General Wards

  A nurse-led program called BEST CARE ICTUS_HC is tested in hospitals without Stroke Units to see if it reduces stroke complications and helps recovery after an acute ischemic or hemorrhagic stroke.

  Recruiting University of Malaga · Antequera, Málaga and 3 other locations · NCT07627399

• Behavioral parent-training with HOT DOCS and DOCS K-5 for caregivers of children ages 0–12.

  This program tests whether group HOT DOCS and DOCS K-5 parent-training classes can help caregivers of children ages 0–12 reduce common challenging behaviors like tantrums, whining, and noncompliance.

  Recruiting University of South Florida · Tampa, Florida · NCT07505381

• Hybrid mirror-primed rehabilitation for unilateral stroke

  This trial will test whether adding enhanced mirror priming to conventional therapy helps adults who had a first-time one-sided stroke at least three months ago improve upper-arm movement.

  Recruiting I-Shou University · Kaohsiung City, Yanchao District · NCT07324278

• Power mobility for very young children with cerebral palsy in early care settings

  This trial tests whether a therapist training program can help providers use powered mobility with children ages 12–32 months with cerebral palsy in home and early intervention settings.

  Recruiting at 2 sites Oregon Health and Science University · Hillsboro, Oregon and 2 other locations · NCT07220590

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.