Neuromuscular re-education versus friction massage for lateral epicondylitis

Effects of Neuromuscular Reeducation Versus Friction Massage in Lateral Epicondylitis: A Randomized Control Trial

Not applicable Interventional Foundation University Islamabad · NCT07004894

This trial will try neuromuscular re-education or friction massage to see which reduces pain and improves function in people aged 25–50 with lateral epicondylitis.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment42 (estimated)
Ages25 Years to 50 Years
SexAll
SponsorFoundation University Islamabad Academic / other
Locations1 site (Islamabad)
Trial IDNCT07004894 on ClinicalTrials.gov

What this trial studies

Participants with diagnosed lateral epicondylitis and at least two positive clinical tests (Cozen's, Maudsley's, or Mill's) will be randomly assigned by coin toss to receive either neuromuscular re-education or a standard friction massage protocol. Outcomes will be measured using the specified clinical tests and standard clinical follow-up to document changes in pain and function. The interventions are delivered in person at a single site by physical therapy staff. The study targets adults aged 25–50 and excludes those with recent elbow fractures, joint instability, active joint disease, or open wounds around the elbow.

Who should consider this trial

Good fit: Ideal candidates are men and women aged 25–50 with a clinical diagnosis of lateral epicondylitis and at least two positive tests among Cozen's, Maudsley's, or Mill's, who do not have recent fractures, joint instability, active joint disease, or open wounds at the elbow.

Not a fit: Patients with recent elbow fractures or dislocations, elbow joint instability, active systemic joint disease, open wounds around the elbow, or those outside the 25–50 age range are unlikely to benefit from the study interventions.

Why it matters

Potential benefit: If successful, the preferred technique could offer a simple, non-surgical way to reduce pain and improve elbow function for people with lateral epicondylitis.

How similar studies have performed: Prior physiotherapy research shows mixed evidence for friction massage and limited but promising data for neuromuscular re-education, so this direct comparison addresses a relatively under-studied question.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Diagnosed cases of lateral epicondylitis
2. Age 25-50 years
3. Both genders
4. Postive tests; cozens, maudsley's, mills (at least any of 2)

Exclusion Criteria:

1. Recent elbow fractures or dislocations
2. Elbow joint instability
3. Active joint disease
4. Open wounds around elbow joints

Where this trial is running

Islamabad

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lateral Epicondylitis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.