Neuromuscular electrical stimulation combined with Leap Motion hand exercises for children with cerebral palsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Children with spastic unilateral or bilateral cerebral palsy and distal upper-extremity involvement (ages 6–15) will receive a program that includes Leap Motion-based interactive exercises, neuromuscular electrical stimulation (NMES), and conventional exercises. Eligibility requires GMFCS and MACS levels I–III, limited spasticity (MAS 0–1+), no botulinum toxin or surgery in the prior 6 months, and the ability to follow verbal instructions. Outcomes focus on upper extremity function, hand use in daily activities, and tolerance of the combined technology-based and conventional interventions. The intervention is delivered at the Physiotherapy and Rehabilitation Department of Istanbul Medipol University.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of spastic unilateral or bilateral cerebral palsy based on clinical and MRI findings.
* Involvement of the distal upper extremity (wrist and/or fingers).
* Aged between 6 and 15 years.
* No history of botulinum toxin injection or surgical intervention to the upper extremity within the past 6 months.
* Gross Motor Function Classification System (GMFCS) levels I-III.
* Manual Ability Classification System (MACS) levels I-III.
* Upper extremity spasticity corresponding to 0, 1, or 1+ on the Modified Ashworth Scale (MAS).
* Passive wrist extension limitation not exceeding 10 degrees.
* Ability to follow verbal instructions (mental level reported as "normal" or "mild mental retardation" in the medical record).

Exclusion Criteria:

* Currently participating in a specific hand rehabilitation program.
* Presence of visual or hearing impairment.
* History of epilepsy.
* Presence of chronic, orthopedic, or systemic conditions that may interfere with participation.
* GMFCS levels IV or V.
* MACS levels IV or V.

Where it's running

• Istanbul Medipol University, Physiotherapy and Rehabilitation Department
  Istanbul, Beykoz, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Hande Özlü Erdoğan, MSc, PhD Candidate, PT
• Email: handeeozlu@gmail.com
• Phone: +905367075474

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Manual Therapy Before Neuromotor Rehab in Children with Cerebral Palsy

  In this pilot study, researchers test whether 30 minutes of lower-limb manual therapy before functional neuromotor therapy helps improve gait and motor performance in children with spastic cerebral palsy.

  Recruiting LIFE - Research and Care Institute - Santa Lucia IRCCS · Roma, Roma · NCT07902466

• Co-designed wrist-hand orthosis for children with neuromotor disorders

  In children aged 6 to 14 with neuromotor conditions after brain injury, researchers are testing a wrist-hand brace designed with input from the kids to see if it fits better and is easier to use than their current orthosis.

  Recruiting IRCCS Eugenio Medea · Bosisio Parini · NCT07861958

• Outcomes of tone-management surgery in children with spastic/dystonic quadriplegia

  This study tests how well intrathecal baclofen pumps and dorsal/ventral rhizotomy help improve movement, comfort, and daily life for kids with severe CP and high muscle tone.

  Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT07817745

• Wearable eye tracking during bimanual tasks in children with cerebral palsy

  This study tests whether wearable eye-tracking glasses can reliably record eye movements while children with CP and typically developing peers perform two-handed tasks.

  Recruiting Samsung Medical Center · Seoul, Seoul · NCT07806994

• Able Kids device: safer gait aid for kids with neurologic gait problems

  This study tests whether the ABLE Kids wearable exoskeleton can be safely used during a 10-session gait training program for children with neurological gait disorders or muscle weakness.

  Recruiting ABLE Human Motion S.L. · Girona, Girona · NCT07745712

• Dorsal Root Electrical Stimulation to Help Spasticity in Children with Cerebral Palsy

  This study tests whether adding dorsal root electrical stimulation during SDR surgery can lessen spasticity in children with cerebral palsy.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07715006

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.