Neurofilament levels in late preterm newborns during early life

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study enrolling up to 15 late preterm newborns to define normal neurofilament concentrations and their early postnatal trajectory. Participants (targeting cohorts at 34, 35, and 36 weeks) will have up to 1 mL of additional blood taken only during routine clinically indicated draws at birth, on day 2, and weekly until 37 weeks of gestation. Samples will be analyzed quantitatively for neurofilament levels and compared across gestational ages and over time. The work is motivated by neurofilaments' role as sensitive biomarkers in conditions such as spinal muscular atrophy and the current lack of normative data in preterm infants.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Gestational age between 34 and 37 weeks of amenorrhea.
* Blood test scheduled for clinical reasons.
* Signed parental consent.

Exclusion Criteria:

* Known neurological disorders.
* Severe congenital malformations.
* Medical contraindication to blood sampling.

Where it's running

• Hopital Citadelle
  Liège, Belgium Recruiting

Study contacts

• Principal investigator: Laurent Servais, MD, PhD — Centre Hospitalier Universitaire de Liege
• Study coordinator: Tamara Dangouloff, PhD
• Email: tamara.dangouloff@uliege.be
• Phone: +33662438138

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.