Neurofeedback treatment for reading difficulties after stroke
Rehabilitation of Reading Deficits in Subacute Stroke Using Functional Magnetic Resonance Imaging (fMRI) Neurofeedback and Motor Imagery
NA · Kessler Foundation · NCT04875936
This study is testing a new brain training method to help stroke survivors improve their reading skills by using real-time brain feedback.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 28 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Kessler Foundation (other) |
| Locations | 1 site (West Orange, New Jersey) |
| Trial ID | NCT04875936 on ClinicalTrials.gov |
What this trial studies
This project aims to enhance cognitive rehabilitation for reading disorders following a stroke by utilizing a novel brain imaging technique known as real-time functional magnetic resonance imaging (fMRI) neurofeedback. Participants will engage in motor imagery exercises while receiving feedback on their brain activity, allowing them to learn how to modulate their brain function to improve reading capabilities. The intervention focuses on reinstating brain activity in the left hemisphere, which is crucial for language processing, to facilitate better reading recovery in stroke patients.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 18 to 80 who have experienced their first left-hemisphere stroke within the last three months and have reading deficits.
Not a fit: Patients who have prior neurological diseases or cannot undergo MRI procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve reading abilities in stroke survivors with acquired dyslexia.
How similar studies have performed: While the use of neurofeedback in rehabilitation is an emerging field, similar studies have shown promising results in enhancing cognitive functions, though this specific approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * First-ever left-hemisphere stroke \< 3 months prior to study recruitment or healthy volunteer * Age: 18 - 80 years old * Fluent and literate in English prior to stroke * Reading deficits, defined as \>3 errors on the Paragraphs test (subtests VIII, IX) of the Reading Comprehension Battery for Aphasia-2nd ed. (RCBA-2) in keeping with the healthy control accuracy criterion of 86-100% correct. Exclusion Criteria: * Inability to consent or complete study tasks * Inability to undergo MRI (e.g., pregnancy, non-MRI compatible implants, claustrophobia) * A history of prior neurological disease (e.g., brain tumor, Alzheimer's disease)
Where this trial is running
West Orange, New Jersey
- Kessler Foundation — West Orange, New Jersey, United States (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Stroke, Dyslexia, Acquired