Neurodynamic sliding mobilization for pain threshold in healthy adults

Effectiveness of Neurodynamic Sliding Mobilisation in the "Slump" Position in Relation to the Perceptible Pain Threshold in Asymptomatic People, a Cross-over Randomised Controlled Trial

This study tests if a specific stretching technique done in a sitting position can help healthy adults feel less pain.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 54 (estimated)
• Ages: 30 Years to 65 Years
• Sex: All
• Sponsor: University Hospital, Rouen (Academic / other)
• Locations: 1 site (Rouen)
• Trial ID: NCT06357715 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of neurodynamic sliding mobilization techniques performed in the 'slump' position on the perceptible pain threshold in asymptomatic individuals. The study aims to understand how these techniques may influence central pain modulation processes, potentially leading to pain reduction. Participants will be randomly assigned to receive treatment in either the 'slump' position or a control position, with the goal of assessing the impact on pain perception. The trial is designed as a cross-over study, allowing each participant to experience both treatment conditions.

Who should consider this trial

Good fit: Ideal candidates are healthy adults aged 30 to 65 who have not previously undergone neurodynamic mobilization techniques.

Not a fit: Patients with existing neurological or neuropathic pain conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into non-invasive techniques for pain management that may benefit individuals with nerve-related pain.

How similar studies have performed: While there is some evidence supporting neurodynamic techniques, this specific approach in the slump position is novel and has not been extensively tested.

Eligibility criteria

Inclusion Criteria:

Subjects aged 30 years or older and less than 65 years;

* Subjects considered naive to neurodynamic mobilisation techniques;
* Volunteers who have read and understood the information letter and have given their written consent to participate in the study;
* Fluent in spoken and read French;
* Effective contraception in women of childbearing age (progestin-only or intrauterine device or tubal ligation) for at least 12 months;
* For postmenopausal women, a confirmatory diagnosis must be obtained (non-drug-induced amenorrhoea for at least 12 months prior to the enrolment visit);
* Subject affiliated to a social security scheme.

Exclusion Criteria:

* Positive slump test on the day of the selection visit (production of asymmetric lumbar symptoms or painful radiations in at least one lower limb or unilateral reduction in physiological knee extension range of motion compared with the contralateral side);
* Neurological and neuropathic pain assessment score (DN4) greater than 4;
* Increase or decrease in sensory function in the lower limb compared with the contralateral side, as measured by Clinical Sensory Testing (CST);
* Any physical exertion of perceived intensity greater than 17 on the Borg 6-20 scale in the 72 hours prior to the trial and during the trial;
* Injury, complaint or symptom affecting the spine (cervical, thoracic, lumbar) and/or lower limb(s) requiring absence from work, school or leisure activities in the 12 months prior to enrolment;
* History of major surgery, injury to the trunk, spine and/or lower limb(s), or history of progressive rheumatic, neurological or oncological pathology;

Where this trial is running

Rouen

• Centre d'investigation clinique CIC ROUEN — Rouen, France (Recruiting)

Study contacts

• Study coordinator: timothée GILLOT, PhD

Conditions Voluntary