Needle aspiration of sperm from the testis in men with azoospermia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of ultrasonically guided Rete Testis needle aspiration to improve sperm production in men diagnosed with azoospermia. The procedure involves aspirating sperm from the Rete Testis, which is expected to contain a significant number of sperm cells, particularly in cases of obstructive azoospermia. Participants will undergo the aspiration procedure, and the samples will be analyzed for sperm viability. If successful, the sperm can be used for cryopreservation or fertilization in assisted reproductive technologies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men with Obstructive/Non-Obstructive Azoospermia who turned to sperm cell aspiration for IVF and were found suitable for TEFNA and signed consent form.

Exclusion Criteria:

* healthy, non-azoospermic men
* men who are unsuitable for the TEFNA procedure
* men who don't sign the Informed Consent

Where it's running

• Hadassah University Medical Center, Ein Kerem
  Jerusalem, Israel Recruiting

Study contacts

• Principal investigator: Benjamin E. Reubinoff, MD PhD — Hadassah University Medical Center
• Study coordinator: Benjamin E. Reubinoff, MD PhD
• Email: benjaminr@ekmd.huji.ac.il
• Phone: 972-2-677-7485

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Identifying genetic variants in non-obstructive azoospermia and primary ovarian insufficiency

  This project will collect DNA from adults with NOA, oligospermia, or POI to try to find gene changes that may cause their infertility.

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• IntelliWell: AI imaging to find ultra-rare sperm in testicular tissue

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• Evaluating Testicular Imaging for Azoospermia Diagnosis

  This study is testing if a special type of ultrasound can help doctors see differences in the tiny tubes in the testicles of men with no sperm and help figure out why that’s happening.

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• Enhancing fertility using stem cell therapy for gonadal dysfunction

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• Using platelet rich plasma to treat infertility in men

  This study is testing if using platelet-rich plasma injections can help men with infertility, specifically those who have had trouble retrieving sperm, improve their chances of successful sperm extraction and IVF.

  Recruiting Stanford University · Stanford, California · NCT05479474

• Maternal MT-ND1 Mutation and Male Infertility

  Researchers look at whether a mitochondrial MT-ND1 variant inherited from mothers is linked to very low or absent sperm production in men with idiopathic infertility.

  Recruiting The Third Affiliated Hospital of Guangzhou Medical University · Guangzhou, Guangdong · NCT07691827

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.