Needle aspiration of sperm from the testis in men with azoospermia
Rete Testis Needle Aspiration for Retrieval of Sperm in Men With Azoospermia Using Ultrasound Guidance
NA · Hadassah Medical Organization · NCT02418832
This study tests if a special needle procedure can help men with no sperm in their semen produce sperm from their testis for use in fertility treatments.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 16 Years to 80 Years |
| Sex | Male |
| Sponsor | Hadassah Medical Organization (other) |
| Locations | 1 site (Jerusalem) |
| Trial ID | NCT02418832 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of ultrasonically guided Rete Testis needle aspiration to improve sperm production in men diagnosed with azoospermia. The procedure involves aspirating sperm from the Rete Testis, which is expected to contain a significant number of sperm cells, particularly in cases of obstructive azoospermia. Participants will undergo the aspiration procedure, and the samples will be analyzed for sperm viability. If successful, the sperm can be used for cryopreservation or fertilization in assisted reproductive technologies.
Who should consider this trial
Good fit: Ideal candidates for this study are men diagnosed with obstructive or non-obstructive azoospermia who are seeking sperm cell aspiration for IVF.
Not a fit: Patients who are healthy and non-azoospermic, or those unsuitable for the TEFNA procedure, will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance sperm retrieval rates for men with azoospermia, improving their chances of fathering children.
How similar studies have performed: While similar approaches have been explored, this specific technique of Rete Testis aspiration is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men with Obstructive/Non-Obstructive Azoospermia who turned to sperm cell aspiration for IVF and were found suitable for TEFNA and signed consent form. Exclusion Criteria: * healthy, non-azoospermic men * men who are unsuitable for the TEFNA procedure * men who don't sign the Informed Consent
Where this trial is running
Jerusalem
- Hadassah University Medical Center, Ein Kerem — Jerusalem, Israel (RECRUITING)
Study contacts
- Principal investigator: Benjamin E. Reubinoff, MD PhD — Hadassah University Medical Center
- Study coordinator: Benjamin E. Reubinoff, MD PhD
- Email: benjaminr@ekmd.huji.ac.il
- Phone: 972-2-677-7485
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Azoospermia, Rete Testis, TEFNA