Nebulized bupivacaine for pain relief in children undergoing cleft palate repair

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness and safety of nebulized bupivacaine as a preemptive analgesic in children undergoing cleft palate repair. Participants will be randomly assigned to receive either two different doses of bupivacaine or a saline placebo. The study aims to determine the optimal dosage for pain management during and after the surgical procedure. Written informed consent will be obtained from the guardians of the children involved in the trial.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children (age 1-7 years) of American Society of Anaesthesiologists physical status (ASA) I-II
* Elective cleft palate repair ± cleft lip surgery under general anesthesia .

Exclusion Criteria:

* Coronary artery disease
* Hypertension
* Developmental delay
* Allergy to study drug

Where it's running

• Assiut university hospital
  Asyut, Assuit, Egypt Recruiting

Study contacts

• Study coordinator: Omar Soliman, MD
• Email: omarmakram347@yahoo.com
• Phone: 01101266040

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effect of a cleft-adapted bottle with a unidirectional valve on milk intake in infants with cleft palate

  This study tests whether using a cleft-adapted bottle with a unidirectional valve helps infants with cleft palate take in more milk than a standard bottle.

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• Palatoplasty techniques using PRF and antibiotic-loaded PRF in cleft palate

  This trial tests whether adding autologous PRF or gentamicin-loaded PRF to primary palatoplasty helps kids with unilateral or bilateral cleft palate heal better and have fewer fistulas than standard surgery.

  Recruiting Al-Thawra Modern General Hospital · Sanaa · NCT07752849

• Comparing pain relief methods after cleft palate surgery in children

  This study is testing whether short-acting or long-acting pain medications work better for managing pain in young children after cleft palate surgery.

  Recruiting Phase 4 Duke University · Durham, North Carolina · NCT06962306

• Furlow palatoplasty with buccal flap for speech in children with cleft palate

  This project compares two palate repair methods to see if Furlow palatoplasty with a buccal myomucosal flap leads to better speech than two-flap palatoplasty in children aged 3–5 with nonsyndromic cleft palate.

  Recruiting Fayoum University · Al Fayyum · NCT06856330

• Comparing two pain management techniques for children undergoing palate surgery

  This study is testing two different pain management techniques for kids aged 6-18 who are having palate surgery to see which one helps them feel less pain after the operation.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT06420336

• Analyzing Velopharyngeal Motor Skills in Children with Cleft Palate Using MRI

  This study is trying to see how well the muscles in the throat work in children with cleft palate to help understand why some still have trouble speaking after surgery.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT06072495

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.