National screening program for chronic obstructive pulmonary disease in China

The National Chronic Obstructive Pulmonary Disease Screening Program in China

This study is testing a national screening program in China to find and help people at risk for chronic obstructive pulmonary disease (COPD) by checking 800,000 participants and managing their care.

Quick facts

• Study type: Observational
• Enrollment: 800000 (estimated)
• Ages: 35 Years to 75 Years
• Sex: All
• Sponsor: China-Japan Friendship Hospital (Academic / other)
• Locations: 1 site (Beijing)
• Trial ID: NCT05480176 on ClinicalTrials.gov

What this trial studies

This program aims to screen and manage chronic obstructive pulmonary disease (COPD) across China by recruiting 800,000 participants from various districts. It will identify high-risk individuals and those with undiagnosed COPD, following standardized clinical guidelines for their management. The study will estimate the prevalence of COPD and track the disease's development and outcomes over time.

Who should consider this trial

Good fit: Ideal candidates are adults aged 35 to 75 who have lived in the survey area for more than six months.

Not a fit: Patients with recent severe cardiac events, mental disorders, or uncontrolled hypertension may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could lead to earlier diagnosis and better management of COPD, improving patient outcomes.

How similar studies have performed: Other studies have shown success in COPD screening and management, indicating that this approach is supported by previous findings.

Eligibility criteria

Inclusion Criteria:

* adults aged between 35 and 75 years;
* residents living in the survey area with more than 6 months in the past year.

Exclusion Criteria:

* experienced myocardial infarction, stroke or shock in the past 3 months;
* experienced severe cardiac insufficiency, severe arrhythmia or unstable angina pectoris in the past 4 weeks;
* experienced massive hemoptysis in the past 4 weeks;
* received chest, abdominal or ophthalmic surgery in the past 3 months;
* have mental disorders (e.g. auditory hallucinations, visual hallucinations, taking antipsychotics, seizures requiring medication, etc.);
* have cognitive impairment (e.g. dementia, comprehension impairment, etc.);
* have uncontrolled hypertension (i.e. systolic blood pressure \> 200 mmHg, diastolic blood pressure \> 100 mmHg);
* present with heart rate \>120 beats/min;
* have aortic aneurysm;
* have severe hyperthyroidism;
* are pregnant or lactating women;
* experienced respiratory infectious diseases (e.g. tuberculosis, influenza, etc.) in the past month.

Where this trial is running

Beijing

• China-Japan Friendship Hospital — Beijing, China (Recruiting)

Study contacts

• Principal investigator: Ting YANG, M.D. — China-Japan Friendship Hospital
• Study coordinator: Jieping LEI, Ph.D.

Conditions Chronic Obstructive Pulmonary Disease; Screening; Spirometry