National registry for neuro-inflammatory diseases in China
China National Registry of Neuro-Inflammatory Diseases: a Prospective Cohort Study
This study is creating a large database to track and understand the experiences of people in China with neuro-inflammatory diseases like multiple sclerosis, to help improve treatment and care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Sex | All |
| Sponsor | Beijing Tiantan Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT05154370 on ClinicalTrials.gov |
What this trial studies
This observational study aims to establish a large prospective cohort database for patients with central nervous system idiopathic inflammatory demyelinating diseases (IDD) in China. It will collect detailed electronic information on demographics, medical history, clinical status, and treatment outcomes of patients diagnosed with conditions such as multiple sclerosis and neuromyelitis optica spectrum disorder. The study seeks to understand the natural course of these diseases, evaluate drug efficacy, and develop standardized follow-up management and treatment guidelines for IDD patients in China.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with any form of idiopathic inflammatory demyelinating disease, regardless of age or sex.
Not a fit: Patients with severe mental illness that prevents them from cooperating with examinations or follow-ups will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the disease progression and treatment efficacy for patients with neuro-inflammatory diseases in China.
How similar studies have performed: While similar cohort studies have been conducted globally, this study is novel as it aims to create the first large nationwide registry for CNS IDD in China.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\. No requirement for age and sex * 2\. Need to meet the diagnosis of at least one IDD (clinically isolated syndrome (CIS)/multiple sclerosis (MS)/neuromyelitis optica spectrum disorder (NMOSD)/MOG antibody-associated disease (MOGAD)/acute disseminated encephalomyelitis (ADEM). * 3\. Signed informed consent form. Exclusion Criteria: * Those with severe mental disease unable to cooperate with the examination and/or follow-up. * Any patient (or the patient's legal representative) who is unable or refuses to sign informed consent.
Where this trial is running
Beijing, Beijing Municipality
- Beijing Tiantan Hospital — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Study coordinator: Fu-Dong Shi
- Email: fshi@tmu.edu.cn
- Phone: 8610-59976585
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.