National registry for monitoring multiple myeloma treatment in Italy

A "Physician & Patient-powered" Cohort Registry

This study is creating a national registry in Italy to track how multiple myeloma is treated and to gather information about patients since 2019.

Quick facts

• Study type: Observational
• Enrollment: 1900 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: Fondazione EMN Italy Onlus (Academic / other)
• Locations: 27 sites (Florence, Firenze and 26 other locations)
• Trial ID: NCT05001087 on ClinicalTrials.gov

What this trial studies

This observational study aims to create a national registry for multiple myeloma in Italy to monitor current clinical practices and describe the standard of care across various hematology centers. It will collect data on patients diagnosed with active or symptomatic multiple myeloma since January 2019, focusing on treatment approaches and patient demographics. The registry will include both a standard epidemiological component and a patient-powered registry to enhance patient involvement and data collection.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older diagnosed with active or symptomatic multiple myeloma since January 2019.

Not a fit: Patients who do not have a diagnosis of multiple myeloma or those diagnosed before January 2019 may not benefit from this study.

Why it matters

Potential benefit: If successful, this registry could improve understanding of treatment practices and outcomes for multiple myeloma patients in Italy, potentially leading to enhanced care standards.

How similar studies have performed: Other countries have successfully established national registries for multiple myeloma, indicating that this approach has been effective in similar contexts.

Eligibility criteria

Inclusion Criteria:

* Patients of both sexes
* Age ≥ 18 years
* Diagnosis of active/symptomatic multiple myeloma (according to CRAB and biological parameters) no earlier than 1st January 2019
* Able and willing to sign an informed consent form

Exclusion Criteria:

* None considered

Where this trial is running

Florence, Firenze and 26 other locations

• A.O.U di Careggi — Florence, Firenze, Italy (Recruiting)
• AOU Ospedali Riuniti Umberto I — Ancona, Italy (Recruiting)
• Policlinico di Bari - Ematologia con Trapianto — Bari, Italy (Not_yet_recruiting)
• Policlinico di Bari — Bari, Italy (Recruiting)
• Policlinico S. Orsola — Bologna, Italy (Recruiting)
• A.O. Spedali Civili di Brescia — Brescia, Italy (Recruiting)
• AOU Policlinico Vittorio Emanuele — Catania, Italy (Recruiting)
• A.O.U Policlinico S. Martino — Genova, Italy (Recruiting)
• ASST Santi Paolo e Carlo — Milan, Italy (Recruiting)
• Fondazione IRCCS Ca' Grande Ospedale Maggiore Policlinico — Milan, Italy (Recruiting)
• Istituto Nazionale Tumori — Milan, Italy (Recruiting)
• Ospedale Niguarda Cà Grande — Milan, Italy (Recruiting)
• Ospedale San Gerardo di Monza — Monza, Italy (Recruiting)
• A.O.U Federico II — Naples, Italy (Not_yet_recruiting)
• Ospedale Maggiore — Novara, Italy (Recruiting)
• A.O.U di Parma — Parma, Italy (Recruiting)
• Policlinico San Matteo Fondazione IRCCS — Pavia, Italy (Recruiting)
• Ospedale "Infermi" — Rimini, Italy (Terminated)
• Ospedale S. Eugenio — Roma, Italy (Recruiting)
• Policlinico Umberto I - Università La Sapienza — Roma, Italy (Recruiting)
• Policlinico Universitario Campus Biomedico — Roma, Italy (Recruiting)
• IRCCS Ospedale Casa Sollievo della Sofferenza — San Giovanni Rotondo, Italy (Recruiting)
• A.O. Santa Maria — Terni, Italy (Recruiting)
• A.O Ordine Mauriziano — Torino, Italy (Recruiting)
• AOU Città della Salute e della Scienza di Torino — Torino, Italy (Recruiting)
• Policlinico Universitario di Udine — Udine, Italy (Recruiting)
• Ospedale di Circolo — Varese, Italy (Recruiting)

Study contacts

• Study coordinator: Mario Boccadoro

Conditions Multiple Myeloma