National registry for liver cancer patients

JADE - Clinical Research Platform on Treatment and Outcome in Patients With Hepatocellular or Cholangiocellular Cancer

Observational iOMEDICO AG · NCT04510740

This study is creating a national registry to track and gather information about patients with liver cancer to help improve treatment and understand their experiences over time.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
Ages18 Years and up
SexAll
SponsoriOMEDICO AG Industry-sponsored
Locations1 site (Multiple Locations)
Trial IDNCT04510740 on ClinicalTrials.gov

What this trial studies

This project establishes a national, prospective, longitudinal cohort study in Germany to create a tumor registry platform for patients with Hepatocellular Carcinoma (HCC) or Cholangiocarcinoma (CCC). It aims to document uniform data on patient characteristics, treatment approaches, and disease progression over a period of up to three years. The registry will also collect patient-reported outcomes and establish a decentralized biobank to support future research. Data on systemic treatments, surgeries, and health-related quality of life will be evaluated throughout the study.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with confirmed HCC or CCC at any stage of the disease.

Not a fit: Patients receiving only best supportive care without any active treatment will not benefit from this study.

Why it matters

Potential benefit: If successful, this registry could enhance understanding of liver cancer treatments and improve patient outcomes through better-informed therapeutic strategies.

How similar studies have performed: Other observational studies have shown success in similar approaches, indicating the potential for valuable insights into treatment patterns and patient outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* Confirmed hepatocellular carcinoma (HCC) or cholangiocarcinoma (CCC) als early, intermediate or advanced/metastatic stage
* Age ≥ 18 years
* Signed and dated informed consent (IC):

  * For participation in the PRO module: Before primary locoregional therapy or start of first systemic treatment
  * For no participation in the PRO module: No later than 8 weeks after primary locoregional therapy or start of first systemic treatment

Exclusion criteria:

Patients treated with best supportive care (BSC) only (i.e. no surgery, no radiotherapy, no ablative procedures, no systemic anti-tumoral therapies)

Where this trial is running

Multiple Locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hepatocellular CarcinomaCholangiocarcinoma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.