Naloxone training program for communities to respond to opioid overdoses

Developing and Testing the Opioid Rapid Response System

Not applicable Interventional University of Missouri-Columbia · NCT06238128

This study is testing a training program to help community members learn how to use naloxone to save lives during opioid overdoses.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1600 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorUniversity of Missouri-Columbia Academic / other
Locations1 site (San Francisco, California)
Trial IDNCT06238128 on ClinicalTrials.gov

What this trial studies

This project aims to implement the Opioid Rapid Response System (ORRS) to enhance community engagement in responding to opioid overdoses. It focuses on training citizens in participating PulsePoint communities on how to effectively use naloxone, a life-saving medication that reverses opioid overdoses. The approach emphasizes targeted strategies rather than widespread distribution, addressing barriers such as access to training and timely responses. By leveraging mobile technology, the program seeks to create a coordinated and efficient response system to combat the opioid epidemic.

Who should consider this trial

Good fit: Ideal candidates for this program are adults aged 18 and older who reside in participating PulsePoint communities and are fluent in English.

Not a fit: Patients who do not live in participating communities, are under 18, or lack access to mobile data and smartphone apps may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could significantly reduce opioid overdose deaths by empowering community members with the knowledge and tools to respond effectively.

How similar studies have performed: Other community-based naloxone training initiatives have shown promise in improving response rates to opioid overdoses, suggesting that this approach could be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Citizens who live in participating PulsePoint communities
* Must to be 18 and older
* Must be fluent in English
* Must have access to the mobile data and able to download and use apps in a smartphone

Exclusion Criteria:

* Citizens who do not live in participating PulsePoint communities
* Under 18-year-old
* Citizens who are not fluent in English
* Citizens who do not have access to mobile data and unable to download and use apps in a smartphone.

Where this trial is running

San Francisco, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Opioid Overdosenaloxone trainingCommunity-engagement
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.