Clinical trial Recruiting at 1 site Observational

Nailfold Capillaroscopy in People with Psoriasis

Official title: Nailfold Capillaroscopic Changes in Psoriasis and Its Correlation With Disease Severity

Run by Al-Azhar University · NCT07693595 · Data updated 2026-11-12

This study tests whether nailfold capillaroscopy findings relate to psoriasis severity and differ by psoriasis type and skin type.

Quick facts

Study typeObservational
SexAll
Enrollment100 (estimated)
SponsorAl-Azhar University
Academic / other
Locations1 site (Cairo, Cairo Governorate)
StatusRecruiting
StartedAugust 1, 2026
Main results expectedNovember 1, 2026
Study endsDecember 1, 2026
Registry record updatedJuly 31, 2026
Trial IDNCT07693595 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults with clinically diagnosed psoriasis attending the specified Cairo hospitals who are not excluded by the criteria.

Probably not a fit

Patients with comorbidities or factors listed in the exclusion criteria may not experience direct benefits from the study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will enroll people with psoriasis at dermatology clinics and perform nailfold capillaroscopy to identify microvascular changes. Researchers will compare capillaroscopic findings with disease severity and examine differences across clinical psoriasis types and Fitzpatrick skin phototypes. The study will collect clinical assessments and capillaroscopy results to explore possible associations. No intervention will be given beyond the imaging procedure, and participants will be observed in an outpatient setting.

Why it matters

Potential benefit: If successful, the findings may improve understanding of how microvascular changes relate to psoriasis severity and subtypes.

How similar studies have gone: Previous research in other conditions has used capillaroscopy to detect microvascular changes, but results in psoriasis are exploratory and not yet definitive.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients clinically diagnosed with psoriasis.

Exclusion Criteria:

* Patients with connective tissue diseases (e.g., systemic sclerosis, SLE)
* Diabetes mellitus or peripheral vascular disease
* Current smokers
* Pregnant or lactating women
* Recent use of vasodilators or beta-blockers
* Manual workers exposed to vibrating tools

Where it's running

  • Al-Hussein University Hospital & Sayed Galal University Hospital
    Cairo, Cairo Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.