Nailfold Capillaroscopy in People with Psoriasis
Official title: Nailfold Capillaroscopic Changes in Psoriasis and Its Correlation With Disease Severity
Run by Al-Azhar University · NCT07693595 · Data updated 2026-11-12
This study tests whether nailfold capillaroscopy findings relate to psoriasis severity and differ by psoriasis type and skin type.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Al-Azhar University Academic / other |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Status | Recruiting |
| Started | August 1, 2026 |
| Main results expected | November 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | July 31, 2026 |
| Trial ID | NCT07693595 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with clinically diagnosed psoriasis attending the specified Cairo hospitals who are not excluded by the criteria.
✕Probably not a fit
Patients with comorbidities or factors listed in the exclusion criteria may not experience direct benefits from the study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will enroll people with psoriasis at dermatology clinics and perform nailfold capillaroscopy to identify microvascular changes. Researchers will compare capillaroscopic findings with disease severity and examine differences across clinical psoriasis types and Fitzpatrick skin phototypes. The study will collect clinical assessments and capillaroscopy results to explore possible associations. No intervention will be given beyond the imaging procedure, and participants will be observed in an outpatient setting.
Why it matters
Potential benefit: If successful, the findings may improve understanding of how microvascular changes relate to psoriasis severity and subtypes.
How similar studies have gone: Previous research in other conditions has used capillaroscopy to detect microvascular changes, but results in psoriasis are exploratory and not yet definitive.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients clinically diagnosed with psoriasis. Exclusion Criteria: * Patients with connective tissue diseases (e.g., systemic sclerosis, SLE) * Diabetes mellitus or peripheral vascular disease * Current smokers * Pregnant or lactating women * Recent use of vasodilators or beta-blockers * Manual workers exposed to vibrating tools
Where it's running
-
Al-Hussein University Hospital & Sayed Galal University Hospital
Cairo, Cairo Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Ahmed H Nouh, Asst Prof Derm & Venereol
- Email: Dr.ahmednouh@azhar.edu.eg
- Phone: +201062034079
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.