Clinical trial Recruiting at 1 site Interventional Ages 2 and up

Nail bed repair for nail bed injuries: does fixing the nail bed help outcomes?

Official title: Nail Bed Repair RCT

Run by Stanford University · NCT07388823 · Data updated 2026-11-12

In people with nail bed injuries, this study tests whether repairing the nail bed leads to better results than just irrigation and dressing.

Quick facts

Study typeInterventional
Ages2 Years and up
SexAll
Enrollment100 (estimated)
SponsorStanford University
Academic / other
Locations1 site (Palo Alto, California)
StatusRecruiting
StartedJune 1, 2026
Main results expectedOctober 31, 2030
Study endsOctober 31, 2030
Registry record updatedJuly 20, 2026
Trial IDNCT07388823 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 2 years or older with disruption of the nail plate or a laceration near the nail that may affect the nail matrix or a subungual hematoma greater than 50%.

Probably not a fit

Patients with missing nail bed tissue, prior injury to the affected nail, or injuries requiring other surgical treatment may not benefit from the nail bed repair approach studied.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial compares two treatments for nail bed injuries: nail bed repair versus irrigation and dressing alone. Participants are randomized to one of the two approaches and outcomes are tracked to see which method provides better healing and function. The study is conducted at Stanford University and aims to enroll children as young as 2 years old and adults with specific nail injuries. Results will inform whether repair offers a meaningful advantage over dressing and irrigation alone.

Why it matters

Potential benefit: If successful, patients may experience improved nail growth, appearance, and function after injury.

How similar studies have gone: Prior evidence in similar soft-tissue and nail injuries suggests repair can improve outcomes, but dedicated randomized data for this specific nail bed comparison are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients 2+ years of age
* presenting with disruption of nail plate or laceration adjacent to nail which appears that it may extend into the nail matrix OR subungual hematoma \>50% of nail
* presenting within 3 days of acute injury

Exclusion Criteria:

* missing (e.g. avulsed) nail bed or segment of nail bed,
* prior injury to affected nail
* need for surgical treatment of injury (e.g. underlying operative fracture)

Where it's running

  • Stanford University
    Palo Alto, California, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.