Myofunctional Therapy for Obstructive Sleep Apnea

Effect of Myofunctional Therapy on Outcomes in Mild to Moderate Sleep Apnea

Not applicable Interventional VA Office of Research and Development · NCT04608552

This study is testing whether orofacial exercises can help veterans with mild-to-moderate obstructive sleep apnea breathe better and feel improved compared to a fake treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment240 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorVA Office of Research and Development Federal
Locations1 site (San Diego, California)
Trial IDNCT04608552 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of Orofacial Myofunctional Therapy (OMT) on veterans diagnosed with mild-to-moderate Obstructive Sleep Apnea (OSA). The research aims to determine whether OMT can improve OSA severity, patient functional status, and symptoms compared to a sham treatment. OMT involves specific exercises targeting the oral and oropharyngeal regions to enhance breathing and airway function during sleep. The study is designed to provide an alternative therapeutic option for patients who struggle with conventional OSA treatments.

Who should consider this trial

Good fit: Ideal candidates are veterans aged 18 and older with a confirmed diagnosis of mild-to-moderate OSA who are receiving care at the VA San Diego Healthcare System.

Not a fit: Patients with cognitive impairments, low health literacy, or those residing outside of San Diego County may not benefit from this study.

Why it matters

Potential benefit: If successful, this therapy could offer a non-invasive alternative for managing mild-to-moderate OSA, improving patient adherence and outcomes.

How similar studies have performed: While the approach of using myofunctional therapy for OSA is relatively novel, similar rehabilitative therapies have shown promise in other studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Mild-to-moderate OSA
* Entry criteria are as inclusive as possible and operationalized as follows: age\>18 years old
* Confirmed diagnosis of OSA
* Having chronic symptoms per screening symptom checklist
* Fluency in English
* Must be getting care the VA San Diego Healthcare System

Exclusion Criteria:

* Cognitive impairment sufficient to cause inability to complete the protocol (per medical chart review)
* Low health literacy
* Residence in a geographical area outside of San Diego County
* Fatal comorbidity (life expectancy \<6 months as indicated by treating physician)
* Significant documented substance/chemical abuse

Where this trial is running

San Diego, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obstructive Sleep ApneaSleep ApneaMyofunctional TherapyChronic Disease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.