Clinical trial Recruiting at 1 site Interventional Ages 20 to 40

Myofascial release therapy for knee pain related to patellar tracking issues

Official title: Effects of Compressive Myofascial Release of the Vastus Lateralis on Lateral Patellar Tracking in Patients With Patellofemoral Pain Syndrome

Run by Riphah International University · NCT06875804 · Data updated 2026-11-12

This study is trying out a special massage technique to see if it can help young adults with knee pain from patellar tracking issues feel better and move more easily.

More Patellofemoral Pain Syndrome trials

Quick facts

Study typeInterventional
Ages20 Years to 40 Years
SexAll
Enrollment24 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedJanuary 2, 2025
Main results expectedSeptember 2, 2025
Study endsSeptember 15, 2025
Registry record updatedMarch 13, 2025
Trial IDNCT06875804 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 20 to 40 who have been diagnosed with Patellofemoral Pain Syndrome and exhibit specific symptoms related to patellar tracking.

Probably not a fit

Patients with a history of knee surgery, other knee conditions, or contraindications to myofascial release therapy are unlikely to benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of compressive myofascial release on the vastus lateralis muscle to improve lateral patellar tracking in patients with Patellofemoral Pain Syndrome (PFPS). PFPS is characterized by anterior knee pain and is often exacerbated by activities like squatting and running. The study employs a randomized controlled trial design, enrolling patients aged 20 to 40 diagnosed with PFPS and exhibiting specific symptoms and radiographic findings. The intervention includes baseline physical therapy treatment alongside the myofascial release technique aimed at alleviating muscle tightness and restoring optimal function.

Why it matters

Potential benefit: If successful, this approach could significantly reduce knee pain and improve mobility for patients suffering from Patellofemoral Pain Syndrome.

How similar studies have gone: While myofascial release techniques have been explored in various contexts, this specific application to PFPS and lateral patellar tracking is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age group between 20 to 40 years
* Male and female gender
* Diagnosed cases of Patellofemoral syndrome
* Participants with positive J sign and Clarke's test
* Pain provoked during knee loading physical activity, such as jumping, running, squatting, or going up or down stairs in last 3 months
* Presence of excessive lateral patellar tracking on axial view radiographs

Exclusion Criteria:

* History of knee surgery in the past year.
* Any contraindications to myofascial release therapy, such as active infections, open wounds.
* Presence of hip pathology or other knee conditions such as ligament tears, meniscal injuries, Osgood-Schlatter or Sinding-Larsen-Johanssen syndrome or jumpers knee
* Participants with a history of trauma or repetitive episodes of patellar subluxation or dislocation
* Use of intra-articular corticosteroid injections
* Presence of auto-immune disorder (spondylolisthesis, spondylitis, Rheumatoid arthritis etc.) other than knee OA or systemic conditions such as severe cardiovascular disease

Where it's running

  • Social Security Hospital
    Lahore, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.