Multisensory immersive VR plus treadmill for post-stroke motor and cognitive recovery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-blind randomized controlled trial compared multisensory immersive VR combined with treadmill training versus treadmill training alone in adults after a first stroke. Participants received 20 minutes per day of training for 30 days, with baseline and endpoint assessments of motor, cognitive, emotional, and daily living function. Motor outcomes included Fugl-Meyer, muscle strength/tone, Berg balance, and three-dimensional gait analysis, while cognitive testing included MMSE, MoCA, and other standardized cognitive measures; brain function was measured with fNIRS and fMRI. The trial enrolled ambulatory patients with moderate lower-extremity impairment and preserved basic cognition, and outcomes focused on changes in motor and cognitive performance after the intervention period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. The first onset of stroke is diagnosed and confirmed according to the requirements of stroke
2. The Fugl-Meyer Assessment of Lower Extremity (FMA-LE) is less than 34.
3. 18-85 years of age.
4. Able to walk with minor assistance
5. MMSE score of 20-30 and ability to understand and follow instructions during the trial
6. Able to sign an informed consent form.

Exclusion Criteria:

1. Severe visual or hearing impairments.
2. Pregnant or breastfeeding women.
3. Patients with unrepaired cranial bone flaps or metallic implants following brain surgery.
4. Presence of other conditions affecting lower limb motor function, such as osteoarthritis or recent lower limb fractures.
5. History of severe psychiatric disorders, other neurological diseases, acute cardiopulmonary dysfunction, multiple organ failure, brain tumours, or epilepsy.

Where it's running

• The First Affiliated Hospital of Chongqing Medical University, First Branch
  Chongqing, Chongqing Municipality, China Recruiting

Study contacts

• Study coordinator: Dingqun Bai
• Email: baidingqun2014@163.com
• Phone: 023-89011334

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.