Multimodal treatment for provoked vulvodynia in young women

Young Vulvodynia: Effect and Efficacy of a Multimodal Treatment for Young Women With Vulvar Pain

Not applicable Interventional Region Örebro County · NCT07092332

This project will try a combined treatment (including cognitive behavioral therapy and other approaches) to see if it reduces pain and improves sexual and emotional health in young women aged 15–23 with provoked vulvodynia.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment15 (estimated)
Ages15 Years to 23 Years
SexFemale
SponsorRegion Örebro County Academic / other
Locations1 site (Örebro)
Trial IDNCT07092332 on ClinicalTrials.gov

What this trial studies

This is a sequential single-case experimental AB design conducted at a youth guidance center in Örebro, Sweden, using randomized baseline lengths of 4, 5, or 6 weeks followed by a 25-week treatment period. Participants complete brief self-assessments twice weekly via the m-Path app during baseline and treatment, plus comprehensive questionnaires before, after, and at six months. Inclusion requires biological females aged 15–23 with a diagnosis of provoked vulvodynia and excludes those with prioritized severe psychological issues, recent childbirth, ongoing pregnancy, PTSD related to sexual trauma, insufficient Swedish, or no experience of vaginal sex. Outcomes align with the Core Outcome Set in vulvodynia and focus on pain as the primary measure alongside psychological, sexual, and relational health.

Who should consider this trial

Good fit: Ideal candidates are biological females aged 15 to 23, diagnosed with provoked vulvodynia, who have experience of vaginal sex and can communicate in Swedish and attend the Örebro youth clinic.

Not a fit: Patients with severe mental-health problems that need priority treatment, current pregnancy or childbirth within the past year, PTSD related to sexual trauma, insufficient Swedish language skills, or no experience of vaginal sex may not benefit or be eligible for this program.

Why it matters

Potential benefit: If successful, the multimodal approach could reduce provoked vulvar pain and improve sexual and psychological well‑being in young women.

How similar studies have performed: Multimodal programs combining CBT and pelvic health approaches have shown promising but mixed results in adults, and applying a randomized single-case design to young women is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Biological sex female
* 15-23 years of age
* Diagnosed with Provoked vulvodynia

Exclusion Criteria:

* Severe psychological issues that should be prioritized before vulvodynia treatment (e.g., substance abuse, psychosis)
* Ongoing pregnancy
* Childbirth within the last year
* Post-traumatic stress disorder (PTSD) related to sexual trauma
* Insufficient mastery of the Swedish language
* No experience of vaginal sex, as vaginismus might be suspected, which requires different treatment

Where this trial is running

Örebro

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions VulvodyniaProvoked VulvodyniaMultimodal TreatmentCognitive Behavior TherapySingle-Case Experimental DesignChronic PainAdolescentEmerging Adulthood
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.