Multimodal sensing and machine learning to detect mental and social states

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The program develops integrated hardware and software: a skin‑like wearable that measures physiological and biochemical signals, a conversational virtual human platform to evoke natural social responses, audiovisual affect recognition software, synchronization tools, and machine‑learning methods to model the combined data. Researchers will record responses during virtual social interactions and controlled challenges such as the cold pressor test in healthy volunteers and in patients who already have clinically implanted intracranial EEG (iEEG) electrodes. The iEEG recordings are from electrodes placed for clinical seizure localization and are unrelated to clinical care changes. The goal is to demonstrate that multimodal signals can be synchronized and modeled to reveal moment‑to‑moment mental and social states.

Why it matters

Who can join: the full rules

For the healthy population, all subjects over the age of 18 who are able and willing to give informed consent will be eligible.

For the epilepsy population, inclusion criteria are:

* Patients who suffer from drug-resistant epilepsy and already have intracranial EEG (iEEG) electrodes implanted based on clinical criteria for their standard seizure localization (unrelated to our study) will be eligible. Most patients are healthy adults outside of their epilepsy.
* Subjects \>= 18 are only included in this study.
* All patients with the above conditions and with already-implanted electrodes who are willing to participate and able to cooperate and follow research instructions will be recruited.

Where it's running

• Rancho Los Amigos National Rehabilitation Center
  Downey, California, United States Recruiting
• University of Southern California
  Los Angeles, California, United States Recruiting

Study contacts

• Principal investigator: Maryam Shanechi, PhD — University of Southern California

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.