Multidomain intervention to improve cognitive function in older adults

Effects of Multidomain Intervention on Cognitive Function in Community-dwelling Elderly

Not applicable Interventional Chang Gung Memorial Hospital · NCT06180161

This study is testing a new program that helps older adults with memory problems improve their thinking skills and overall health by focusing on things like exercise, nutrition, and social support.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment120 (estimated)
Ages60 Years and up
SexAll
SponsorChang Gung Memorial Hospital Academic / other
Locations1 site (Taoyuan)
Trial IDNCT06180161 on ClinicalTrials.gov

What this trial studies

This study aims to address cognitive decline in community-dwelling elderly individuals by implementing a multidomain intervention that targets various health factors such as mobility, nutrition, and psychosocial well-being. Participants will include older adults aged 60 and above who report cognitive-related issues but do not have a dementia diagnosis. The intervention seeks to enhance cognitive abilities and overall health through a comprehensive approach that combines multiple strategies. By focusing on prevention and early intervention, the study hopes to improve the quality of life for older adults.

Who should consider this trial

Good fit: Ideal candidates for this study are community-dwelling adults aged 60 and older who experience subjective cognitive decline or mild cognitive impairment but do not have a dementia diagnosis.

Not a fit: Patients with unstable medical conditions or those diagnosed with any type of dementia may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance cognitive function and quality of life for elderly individuals at risk of cognitive decline.

How similar studies have performed: Previous studies have shown promising results with multidomain interventions targeting cognitive decline, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥ 60 years old
2. Mini-Mental State Examination (MMSE) score \> 20 (Folstein et al., 1975), able to follow instructions and participate in activities
3. With self-reported or caregiver-reported memory or cognitive-related problems
4. No diagnosis of any type of dementia

Exclusion Criteria:

1. Unstable medical condition that would prevent safe participation in exercise training (e.g., myocardial infarction, heart failure, recent cardiac surgery, severe asthma, concomitant neurological disorders, or joint deformities)
2. Participation in other studies
3. Inability to provide informed consent

Where this trial is running

Taoyuan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cognitive Decline
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.