Multidisciplinary pain management program for breast cancer survivors

A Randomized Controlled Trial (RCT) to Determine the Efficacy of a Multidisciplinary CBT Based Pain Management Program for the Treatment of Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) in Breast Cancer Survivors

Not applicable Interventional Mayo Clinic · NCT06831838

This study tests a new pain management program using therapy for breast cancer survivors who have muscle and joint pain from their medication to see if it helps them feel better and stick to their treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment115 (estimated)
Ages18 Years and up
SexAll
SponsorMayo Clinic Academic / other
Locations1 site (Jacksonville, Florida)
Trial IDNCT06831838 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of a multidisciplinary cognitive behavioral therapy (CBT) based pain management program specifically designed for breast cancer survivors experiencing Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS). The program aims to reduce pain, cognitive complaints, psychological distress, and improve functional status, thereby enhancing adherence to Aromatase Inhibitor medications compared to standard care. The study will also identify predictors of improvement in these areas following participation in the program.

Who should consider this trial

Good fit: Ideal candidates for this study are breast cancer survivors aged 18 and older with stage 0-III hormone receptor-positive breast cancer who are seeking strategies to manage their symptoms.

Not a fit: Patients with stage 4 hormone receptor-positive breast cancer are unlikely to benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve the quality of life for breast cancer survivors by alleviating pain and psychological distress.

How similar studies have performed: Other studies have shown promising results with multidisciplinary approaches to pain management in cancer survivors, indicating potential success for this program.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* At least 18 years old
* ECOG ≤ 2
* Stage 0-III HR+ breast cancer in need of strategies to reduce symptoms and improve quality of life

Exclusion Criteria:

• Less than 18 years of age.

\- Stage 4 HR+ breast cancer

Where this trial is running

Jacksonville, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.