Clinical trial Recruiting at 9 sites Observational

Multicenter registry for adults with spontaneous subarachnoid hemorrhage

Official title: Multicenter Registry of Patients With Subarachnoid Hemorrhage

Run by UMC Utrecht · NCT07482124 · Data updated 2026-11-12

This project collects detailed information from adults who had a spontaneous subarachnoid hemorrhage to see which treatments and care patterns lead to better outcomes.

Quick facts

Study typeObservational
SexAll
Enrollment1000 (estimated)
SponsorUMC Utrecht
Academic / other
Locations9 sites (Nijmegen, Gelderland and 8 other locations)
StatusRecruiting
StartedFebruary 12, 2024
Main results expectedAugust 1, 2026
Study endsFebruary 1, 2028
Registry record updatedMarch 19, 2026
Trial IDNCT07482124 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 or older with spontaneous subarachnoid hemorrhage confirmed by non-contrast head CT showing blood in the basal cisterns or major fissures, or by spectrophotometric xanthochromia of cerebrospinal fluid, including aneurysmal and other specified nontraumatic etiologies.

Probably not a fit

Patients with traumatic, neoplastic, infection-related (except mycotic aneurysms), iatrogenic, or isolated convexity subarachnoid hemorrhage, and those not treated at the participating centers, would not be eligible and are unlikely to benefit directly from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational multicenter registry that enrolls adults with spontaneous subarachnoid hemorrhage confirmed by CT or cerebrospinal fluid analysis. Participating centers in the Netherlands will record patient characteristics, diagnostic findings, treatments, complications, and functional outcomes. The registry will combine these data to identify which treatment strategies and clinical factors are associated with better or worse recovery. There are no experimental interventions; the project uses real-world clinical data to guide future care and research.

Why it matters

Potential benefit: If successful, the registry could improve future patient care by identifying treatments and care patterns that produce better outcomes after subarachnoid hemorrhage.

How similar studies have gone: Other national and international SAH registries and cohort studies have previously identified important prognostic factors and influenced clinical practice, so this effort builds on established registry approaches.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Spontaneous subarachnoid hemorrhage with blood in the basal cisterns and/or major fissures on non-contrast head computed tomography (CT), or xanthochromia of cerebrospinal fluid confirmed by spectrophotometric analysis.
* Eligible etiologies/patterns:

  * Aneurysmal SAH
  * SAH from other intracranial vascular malformation (e.g. AVM, dural AVF)
  * Perimesencephalic SAH
  * Non-perimesencephalic angiogram negative SAH
  * SAH from intracranial artery dissection

Exclusion Criteria:

* Traumatic, neoplastic, infection related (except mycotic aneurysms), or iatrogenic SAH
* Isolated convexity SAH

Where it's running

  • Radboud University Medical Center
    Nijmegen, Gelderland, Netherlands
    Recruiting
  • Maastricht University Medical Center+
    Maastricht, Limburg, Netherlands
    Recruiting
  • Elisabeth-Tweesteden Hospital
    Tilburg, North Brabant, Netherlands
    Recruiting
  • Amsterdam University Medical Center
    Amsterdam, North Holland, Netherlands
    Recruiting
  • Isala
    Zwolle, Overijssel, Netherlands
    Recruiting
  • University Medical Center Groningen
    Groningen, Provincie Groningen, Netherlands
    Recruiting
Show 3 more locations
  • Erasmus University Medical Center
    Rotterdam, South Holland, Netherlands
    Recruiting
  • Haaglanden Medical Center
    The Hague, South Holland, Netherlands
    Recruiting
  • Utrecht University Medical Center
    Utrecht, Utrecht, Netherlands
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.