Multicenter registry for adults with spontaneous subarachnoid hemorrhage
Official title: Multicenter Registry of Patients With Subarachnoid Hemorrhage
Run by UMC Utrecht · NCT07482124 · Data updated 2026-11-12
This project collects detailed information from adults who had a spontaneous subarachnoid hemorrhage to see which treatments and care patterns lead to better outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | UMC Utrecht Academic / other |
| Locations | 9 sites (Nijmegen, Gelderland and 8 other locations) |
| Status | Recruiting |
| Started | February 12, 2024 |
| Main results expected | August 1, 2026 |
| Study ends | February 1, 2028 |
| Registry record updated | March 19, 2026 |
| Trial ID | NCT07482124 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with spontaneous subarachnoid hemorrhage confirmed by non-contrast head CT showing blood in the basal cisterns or major fissures, or by spectrophotometric xanthochromia of cerebrospinal fluid, including aneurysmal and other specified nontraumatic etiologies.
✕Probably not a fit
Patients with traumatic, neoplastic, infection-related (except mycotic aneurysms), iatrogenic, or isolated convexity subarachnoid hemorrhage, and those not treated at the participating centers, would not be eligible and are unlikely to benefit directly from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational multicenter registry that enrolls adults with spontaneous subarachnoid hemorrhage confirmed by CT or cerebrospinal fluid analysis. Participating centers in the Netherlands will record patient characteristics, diagnostic findings, treatments, complications, and functional outcomes. The registry will combine these data to identify which treatment strategies and clinical factors are associated with better or worse recovery. There are no experimental interventions; the project uses real-world clinical data to guide future care and research.
Why it matters
Potential benefit: If successful, the registry could improve future patient care by identifying treatments and care patterns that produce better outcomes after subarachnoid hemorrhage.
How similar studies have gone: Other national and international SAH registries and cohort studies have previously identified important prognostic factors and influenced clinical practice, so this effort builds on established registry approaches.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Spontaneous subarachnoid hemorrhage with blood in the basal cisterns and/or major fissures on non-contrast head computed tomography (CT), or xanthochromia of cerebrospinal fluid confirmed by spectrophotometric analysis. * Eligible etiologies/patterns: * Aneurysmal SAH * SAH from other intracranial vascular malformation (e.g. AVM, dural AVF) * Perimesencephalic SAH * Non-perimesencephalic angiogram negative SAH * SAH from intracranial artery dissection Exclusion Criteria: * Traumatic, neoplastic, infection related (except mycotic aneurysms), or iatrogenic SAH * Isolated convexity SAH
Where it's running
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Radboud University Medical Center
Nijmegen, Gelderland, Netherlands Recruiting -
Maastricht University Medical Center+
Maastricht, Limburg, Netherlands Recruiting -
Elisabeth-Tweesteden Hospital
Tilburg, North Brabant, Netherlands Recruiting -
Amsterdam University Medical Center
Amsterdam, North Holland, Netherlands Recruiting -
Isala
Zwolle, Overijssel, Netherlands Recruiting -
University Medical Center Groningen
Groningen, Provincie Groningen, Netherlands Recruiting
Show 3 more locations
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Erasmus University Medical Center
Rotterdam, South Holland, Netherlands Recruiting -
Haaglanden Medical Center
The Hague, South Holland, Netherlands Recruiting -
Utrecht University Medical Center
Utrecht, Utrecht, Netherlands Recruiting
Study contacts
- Study coordinator: P.B. van Wijngaarden, MD
- Email: measure@umcutrecht.nl
- Phone: +88 755 5555
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.