Multi-component approach to control hypertension in rural Pakistan
A Multi-component Intervention for Controlling Hypertension in the Adult Rural Population of Pakistan: a Protocol for a Hybrid Type III Implementation-effectiveness Cluster Randomized Controlled Trial
This study is testing a new way to help people in rural Pakistan manage their high blood pressure through education and support from local health workers.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 3000 (estimated) |
| Ages | 35 Years and up |
| Sex | All |
| Sponsor | Aga Khan University Academic / other |
| Locations | 1 site (Karachi, Sindh) |
| Trial ID | NCT06726057 on ClinicalTrials.gov |
What this trial studies
This project aims to implement a comprehensive hypertension control strategy in rural Sindh, Pakistan, targeting the high prevalence of hypertension and its associated cardiovascular risks. The intervention involves a multi-faceted approach that includes education and support from lady health workers in primary care settings. The study is conducted by Aga Khan University and aims to address the significant undertreatment and underdiagnosis of hypertension in the region. By utilizing proven effective interventions, the project seeks to improve hypertension management in underserved populations.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 35 and older who are residents of the selected clusters and have hypertension.
Not a fit: Patients who are pregnant, have advanced illnesses, or are unable to provide consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce hypertension-related health risks and improve cardiovascular health in rural communities.
How similar studies have performed: Previous community-based trials in Pakistan have shown success with similar multi-component hypertension interventions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥35 years 2. Residents of the selected clusters 3. Have hypertension defined as either: * Persistently elevated BP (Systolic blood pressure \[SBP\] SBP ≥140 mm Hg or diastolic blood pressure \[DBP\] DBP ≥90 mm Hg) from each set of the last two of the three readings from two separate days, where BP measurements on the same day were measured at least 1 minute apart OR * Are on antihypertensive medications Exclusion Criteria: 1. Pregnant women and persons with advanced illness (e.g., those receiving dialysis or with liver failure), cancer 2. Unable to travel to the clinic 3. Unwilling/unable to provide consent
Where this trial is running
Karachi, Sindh
- Aga Khan University — Karachi, Sindh, Pakistan (Recruiting)
Study contacts
- Study coordinator: Zainab Professor, MACC
- Email: samad.zainab@aku.edu
- Phone: +922134864660
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.