MRJP rose tablet candies to improve ovarian function and uterine lining receptivity
Official title: A Randomized Controlled Study on the Effect of MRJPs on Improving Ovarian Function and Endometrial Receptivity
Run by The Fourth Affiliated Hospital of Zhejiang University School of Medicine · NCT07246733 · Data updated 2026-11-12
This will test whether daily oral MRJP rose tablet candies can help women aged 20–45 with diminished ovarian reserve or thin endometrium improve ovarian hormones and make the uterine lining more receptive.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 45 Years |
| Sex | Women only |
| Enrollment | 66 (estimated) |
| Sponsor | The Fourth Affiliated Hospital of Zhejiang University School of Medicine Academic / other |
| Locations | 1 site (Yiwu, Zhejiang) |
| Status | Recruiting |
| Started | July 1, 2025 |
| Main results expected | June 30, 2028 |
| Study ends | July 31, 2028 |
| Registry record updated | November 24, 2025 |
| Trial ID | NCT07246733 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 20–45 with regular menstrual cycles who have diminished ovarian reserve or thin endometrium, are not pregnant or breastfeeding, and are not allergic to royal jelly are the intended participants.
✕Probably not a fit
Women who are allergic to royal jelly, pregnant or breastfeeding, have recent hormone replacement therapy, or have severe chronic or endocrine disorders are excluded and unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, placebo-controlled study gives eligible women either oral MRJP rose tablet candies or a matching placebo and follows them through the treatment period to measure reproductive and safety outcomes. Key measurements include serum hormones (estradiol, progesterone, FSH, LH), endometrial thickness, and expression of estrogen and progesterone receptor genes. Participants with royal jelly allergy, recent hormone therapy, pregnancy, breastfeeding, or severe chronic/endocrine disease are excluded. The trial is conducted at a single site: The Fourth Affiliated Hospital of Zhejiang University School of Medicine in Yiwu, Zhejiang.
Why it matters
Potential benefit: If successful, MRJP candies could offer a non-hormonal, oral option to improve ovarian hormone balance and increase endometrial thickness, potentially supporting fertility.
How similar studies have gone: Preclinical work and small clinical reports suggest MRJPs can affect hormone levels, inflammation, and endometrial parameters, but large randomized trials confirming clinical fertility benefits are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Fertile women, aged 20 to 45 years old, with regular and normal menstrual cycles. Exclusion Criteria: * ① Allergic to royal jelly or its components; ② Suffering from severe chronic diseases or endocrine system disorders; ③ Pregnant or breastfeeding; ④ Undergoing hormone replacement therapy (HRT) within the last month
Where it's running
-
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Yiwu, Zhejiang, China Recruiting
Study contacts
- Study coordinator: Xiaolin Wu
- Email: daringwxl@163.com
- Phone: +86-579-19548878600
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.