MRI study on neck pain in young and middle-aged adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the underlying causes of cervical and shoulder pain in young and middle-aged patients through advanced MRI techniques. Participants will undergo multiple MRI scans using T2-mapping, T1ρ, and DKI sequences, alongside clinical assessments, before and after receiving non-surgical treatments over a period of 12 months. The goal is to identify imaging predictors of treatment efficacy and better understand early disc degeneration that may not be visible on routine MRI. By analyzing the microstructural changes in the intervertebral discs, the study seeks to enhance the diagnosis and management of neck pain.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Neck and shoulder pain, with or without upper limb pain and numbness;
2. Disease duration longer than 2 months
3. Visual analogue score (VAS) ≥ 3
4. Cervical MRI showing cervical disc degeneration, bulge, protrusion, etc.
5. Patients will undergo non-surgical treatment (maxillary occipital traction, massage, etc.)

Exclusion Criteria:

1. Severe trauma and surgery in neck and shoulder region.
2. X-ray or CT showing the severe cervical spine hyperplasia, infection (suppurative, tuberculous), neoplasm (various primary and secondary tumors), rheumatic (rheumatoid arthritis, ankylosing spondylitis), and nuclei pulposus calcification.
3. Cervical MRI revealed organic lesions such as inflammation of the spinal cord, tumors, syringomyelia, etc.
4. Chronic pain in other regions.

Where it's running

• The First Affiliated Hospital of Xi'an Jiaotong University
  Xi'an, Shaanxi, China Recruiting

Study contacts

• Study coordinator: Yuan Wang, M.D.
• Email: wangyuan8003@126.com
• Phone: +8613324598144

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.