MRI study on neck pain in young and middle-aged adults
Applied Research on Young and Middle-aged Patients With Cervical Spondylotic Pain Using T2-mapping, T1ρ and Diffusion Kurtosis Imaging
This study is testing advanced MRI scans to see what causes neck and shoulder pain in young and middle-aged adults and how well non-surgical treatments work for them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT06217029 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the underlying causes of cervical and shoulder pain in young and middle-aged patients through advanced MRI techniques. Participants will undergo multiple MRI scans using T2-mapping, T1ρ, and DKI sequences, alongside clinical assessments, before and after receiving non-surgical treatments over a period of 12 months. The goal is to identify imaging predictors of treatment efficacy and better understand early disc degeneration that may not be visible on routine MRI. By analyzing the microstructural changes in the intervertebral discs, the study seeks to enhance the diagnosis and management of neck pain.
Who should consider this trial
Good fit: Ideal candidates include young and middle-aged adults experiencing neck and shoulder pain for more than two months with evidence of cervical disc degeneration.
Not a fit: Patients with severe trauma, significant organic lesions, or chronic pain in other regions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic methods and treatment strategies for patients suffering from neck pain.
How similar studies have performed: While there have been studies utilizing advanced MRI techniques for similar conditions, this specific approach focusing on early disc degeneration in young adults is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Neck and shoulder pain, with or without upper limb pain and numbness; 2. Disease duration longer than 2 months 3. Visual analogue score (VAS) ≥ 3 4. Cervical MRI showing cervical disc degeneration, bulge, protrusion, etc. 5. Patients will undergo non-surgical treatment (maxillary occipital traction, massage, etc.) Exclusion Criteria: 1. Severe trauma and surgery in neck and shoulder region. 2. X-ray or CT showing the severe cervical spine hyperplasia, infection (suppurative, tuberculous), neoplasm (various primary and secondary tumors), rheumatic (rheumatoid arthritis, ankylosing spondylitis), and nuclei pulposus calcification. 3. Cervical MRI revealed organic lesions such as inflammation of the spinal cord, tumors, syringomyelia, etc. 4. Chronic pain in other regions.
Where this trial is running
Xi'an, Shaanxi
- The First Affiliated Hospital of Xi'an Jiaotong University — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Study coordinator: Yuan Wang, M.D.
- Email: wangyuan8003@126.com
- Phone: +8613324598144
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.