MRI-guided cryoablation for prostate cancer treatment
MRI-Guided Cryoablation for Focal Native Prostate Cancer
This study is testing an FDA-approved MRI-guided cryoablation treatment for men with a specific type of prostate cancer to see how well it works.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 30 Years to 100 Years |
| Sex | Male |
| Sponsor | Mayo Clinic Academic / other |
| Drugs / interventions | Radiation |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT04797039 on ClinicalTrials.gov |
What this trial studies
This research aims to collect data on the MRI-guided cryoablation procedure used to treat focal prostate cancer. Participants diagnosed with biopsy-proven Gleason 7 prostate cancer will undergo this FDA-approved procedure at Mayo Clinic. The study will monitor the technique and evaluate participants' conditions during follow-up visits, which are scheduled according to standard care practices. The focus is on understanding the effectiveness and outcomes of this treatment approach.
Who should consider this trial
Good fit: Ideal candidates are patients with biopsy-proven Gleason 7 prostate cancer who are not suitable for surgery or radiation and have tumors smaller than 2 cm.
Not a fit: Patients with larger tumors, those whose tumors involve critical structures, or those who cannot undergo MRI will not benefit from this study.
Why it matters
Potential benefit: If successful, this could provide a minimally invasive treatment option for patients with focal prostate cancer.
How similar studies have performed: Previous studies have shown success with MRI-guided cryoablation techniques, indicating a promising approach for treating prostate cancer.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with "biopsy proven" Gleason7 prostate cancer referred to Urology and/or Interventional Radiology for treatment * Surgery and/or Radiation is not a desirable alternative therapy at the time of enrollment * Tumor size is \< 2 cm at its largest diameter * Tumor does not encompass the rectal wall or external urethral sphincter * Patient is able to undergo MRI Exclusion Criteria: •
Where this trial is running
Rochester, Minnesota
- Mayo Clinic — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Study coordinator: Desirae Howe-Clayton
- Email: howe.desirae@mayo.edu
- Phone: 507-255-0111
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.