Clinical trial Recruiting at 1 site Observational Ages 18 and up

MRI-based AI to classify and grade renal tumors

Official title: An MRI-Based Study of Intelligent Pathological Subtyping and Grading of Renal Tumors

Run by Cancer Institute and Hospital, Chinese Academy of Medical Sciences · NCT07743749 · Data updated 2026-11-12

This study tests AI methods on MRI data from adults with kidney tumors to see if they can identify tumor type and grade before surgery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment900 (estimated)
SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences
Academic / other
Locations1 site (Beijing)
StatusRecruiting
StartedJanuary 1, 2021
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedAugust 4, 2026
Trial IDNCT07743749 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with a diagnosed renal tumor who have available preoperative renal MRI and a corresponding pathological diagnosis (subtype and grade if applicable).

Probably not a fit

Patients without reliable MRI data or without a complete pathology record may not benefit from the study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational, non-interventional study that uses existing and new MRI data to train and evaluate artificial intelligence models for detecting renal tumors, determining their pathological subtype, and grading them histologically. The research combines retrospective and prospective data, with pathological results serving as the reference standard. No changes to diagnosis or treatment occur, and no extra procedures are required beyond standard care. Data will be de-identified prior to analysis, and multiple MRI sequences may be used to improve model performance. The aim is to support preoperative assessment and personalized management of renal tumors.

Why it matters

Potential benefit: If successful, the approach could assist clinicians in preoperative planning and treatment decisions by providing noninvasive tumor subtype and grade information.

How similar studies have gone: Prior studies in imaging plus AI for renal tumors have shown promise but similar comprehensive MRI-based subtyping and grading is still an evolving area.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18 years or older.
* Patients diagnosed with a renal tumor.
* Availability of preoperative renal magnetic resonance imaging examinations.
* Availability of a corresponding pathological diagnosis, including pathological subtype and, where applicable, histological grade.
* Magnetic resonance images that can be successfully retrieved and are of - - sufficient quality for image analysis.

Exclusion Criteria:

* Absence of renal magnetic resonance imaging data.
* Absence of a corresponding pathological diagnosis or insufficient pathological subtype or grading information.
* Magnetic resonance images that cannot be retrieved, opened, or read.
* Poor image quality that precludes reliable image annotation or artificial intelligence analysis.

Where it's running

  • Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
    Beijing, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.