Moxidectin tablets for treating eyelash infestations
A SINGLE-CENTER, INVESTIGATOR- MASKED, RANDOMIZED, PLACEBO- CONTROLLED, INVESTIGATOR INITIATED STUDY of the SAFETY and EFFICACY of MOXIDECTIN TABLETS for the REDUCTION of DEMODEX EYELASH INFESTATION
This study tests if moxidectin tablets can help people with blepharitis by reducing eyelash infestations caused by Demodex.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Eye Research Foundation, Inc. Industry-sponsored |
| Locations | 1 site (Newport Beach, California) |
| Trial ID | NCT06795165 on ClinicalTrials.gov |
What this trial studies
This study evaluates the safety and efficacy of moxidectin tablets in reducing Demodex eyelash infestation in patients with active blepharitis. It is a single-center, investigator-masked, randomized, placebo-controlled trial designed to assess the treatment's effectiveness compared to a placebo. Participants will receive either the moxidectin treatment or a placebo to determine the impact on their condition.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with active blepharitis accompanied by collarettes.
Not a fit: Patients with other clinically significant eye diseases may not benefit from this treatment.
Why it matters
Potential benefit: If successful, this treatment could significantly alleviate symptoms of blepharitis caused by Demodex infestation.
How similar studies have performed: While there is limited data on moxidectin for this specific use, similar studies targeting Demodex infestations have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Active blepharitis with collarettes - Exclusion Criteria:Other clinically significant eye disease -
Where this trial is running
Newport Beach, California
- Eye Research Foundation, Inc. — Newport Beach, California, United States (Recruiting)
Study contacts
- Study coordinator: David Wirta Principal Investigator, MD
- Email: info@drwirta.com
- Phone: 949-650-1863
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.