Motor performance perception accuracy in people with multiple sclerosis
Assessment of Perceptive Accuracy for Motor Performance in Persons With Multiple Sclerosis
This project tests whether people with multiple sclerosis can accurately judge their performance on prolonged walking and repeated sit-to-stand tasks compared with similar healthy adults.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 88 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Hasselt University Academic / other |
| Locations | 3 sites (Diepenbeek, Belgium and 2 other locations) |
| Trial ID | NCT07175792 on ClinicalTrials.gov |
What this trial studies
This observational project compares self-reported beliefs about motor ability with objective performance during two newly designed tasks: prolonged walking and repeated sit-to-stand. People with MS and age- and gender-matched healthy controls complete questionnaires (physical activity, sleep, self-efficacy, mood, fatigue, interoception), cognitive and sensorimotor tests, and functional performance tests while wearable IMUs record movement. Perceptual judgments are collected and compared to measured outcomes across up to three testing days. The goal is to identify subgroups of people with MS who misjudge their motor performance and might need tailored interventions beyond standard care.
Who should consider this trial
Good fit: Adults 18–70 with a confirmed MS diagnosis who can walk for six minutes without rest and repeatedly perform sit-to-stand transitions without hand support are ideal candidates.
Not a fit: People who cannot safely walk six minutes, require a walking aid, have significant lower-limb musculoskeletal problems, recent relapse within one month, or cognitive impairment preventing instruction comprehension are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the results could identify people with MS who misjudge their motor abilities so clinicians can provide targeted rehabilitation or safety strategies.
How similar studies have performed: Prior studies have noted altered self-perception of motor function in neurological disorders, but applying these specific prolonged-task perception paradigms in MS is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age between 18 and 70 years old * ability to walk for 6 minutes without rest and without the need of a walking aid * ability to repeatedly perform the sit to stand transitions on a standard chair (43cm seat height) without hand support For People with Multiple Sclerosis group * a diagnosis of MS (2017 revisions of the McDonalds criteria) * no disease relapses \>1 month preceding the start of the study Exclusion Criteria: * cognitive impairment hindering understanding of study instructions * ongoing or suspected pregnancy * musculoskeletal disorders in the lower limbs * cardiovascular red flags for exercise (screened with Physical Activity Readines Questionnaire) * other diagnosis for neurological or metabolic disease limiting the full execution of the tests
Where this trial is running
Diepenbeek, Belgium and 2 other locations
- Reval — Diepenbeek, Belgium, Belgium (Recruiting)
- Noorderhart Revalidatie & MS — Overpelt, Belgium, Belgium (Recruiting)
- Nationaal MS-Centrum Melsbroek — Steenokkerzeel, Belgium, Belgium (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.