Motivational interviewing to help veterans at high risk for suicide

Motivational Interviewing to Address Suicidal Ideation: A Randomized Controlled Trial With Suicidal Veterans

Not applicable Interventional VA Office of Research and Development · NCT05256940

This study is testing a new approach called Motivational Interviewing to see if it can help veterans at high risk for suicide feel more motivated to live compared to regular care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment470 (estimated)
Ages18 Years and up
SexAll
SponsorVA Office of Research and Development Federal
Locations3 sites (Canandaigua, New York and 2 other locations)
Trial IDNCT05256940 on ClinicalTrials.gov

What this trial studies

This project aims to conduct a randomized control trial involving 470 veterans to evaluate the effectiveness of a revised version of Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) in reducing suicidal ideation and attempts compared to enhanced usual care. The MI-SI-R intervention consists of three sessions delivered in-person, virtually, or by telephone, focusing on increasing the motivation to live among veterans experiencing suicidal crises. Participants will be randomly assigned to receive either MI-SI-R plus enhanced usual care or enhanced usual care alone, with follow-up assessments conducted at 1, 3, 6, and 12 months post-randomization to measure outcomes. The study is designed to provide insights into effective interventions for high-risk veterans and improve their mental health outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are veterans aged 18 and over who have recently experienced suicidal crises and are able to provide informed consent.

Not a fit: Patients with current psychosis, active mania, dementia, or impaired decision-making capacity may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce suicidal ideation and attempts among high-risk veterans.

How similar studies have performed: Preliminary studies have shown success with similar approaches, indicating a potential for positive outcomes in this trial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Veteran status,
* admitted to an inpatient unit, referred by a suicide prevention coordinator, or identified as high-risk via data extraction,
* age 18 and over,
* English speaking and reading, and
* ability to understand the study and provide informed consent,
* high-risk status confirmed by suicide attempt within a month on the Columbia- Suicide Severity Rating Scale or a score \> 5 on the Scale for Suicidal Ideation

Exclusion Criteria:

* current psychosis,
* active mania,
* dementia,
* impaired decision making capacity, and
* institutionalization due to hospitalization in a non-VA facility, jail, or prison.

Where this trial is running

Canandaigua, New York and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Suicide, AttemptedSuicidal Ideationveteransmotivational interviewing
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.