Motion-controlled mobile games to improve thinking in people with schizophrenia
The Effect of a 2-month Somatic Serious Games on the Cognition of Schizophrenia Patients
This project will try a motion-based smartphone game to improve thinking skills in adults with stable schizophrenia.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 84 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Shanghai Mental Health Center Academic / other |
| Locations | 1 site (Shanghai) |
| Trial ID | NCT07557381 on ClinicalTrials.gov |
What this trial studies
Researchers developed a somatosensory interactive game that uses the gyroscope of mobile devices to train multiple cognitive domains relevant to schizophrenia. Adults with ICD-10 schizophrenia who are clinically stable and able to use a smartphone will be randomized to the game-based intervention versus usual care or control conditions. Standardized cognitive tests will be administered before and after the intervention to measure changes in attention, memory, and other cognitive functions. The trial is designed to evaluate both effectiveness and feasibility in a hospitalized Shanghai patient population.
Who should consider this trial
Good fit: Ideal candidates are adults 18–45 with ICD-10 schizophrenia who are clinically stable, can use a smartphone or tablet, have basic education, and are registered and hospitalized in the participating Shanghai mental health wards.
Not a fit: Patients with acute psychosis, severe motor or sensory impairments, inability to use mobile devices, those outside the age range, or not registered/hospitalized at the participating Shanghai centers are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, the game could improve memory, attention, and everyday thinking while making cognitive rehabilitation more engaging and easier to access.
How similar studies have performed: Previous small studies of serious games and sensory-interactive interventions have shown promising cognitive and engagement benefits, but large randomized trials in schizophrenia are still limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Registered in the Shanghai Mental Health Information Management System and hospitalized in the designated district-level mental health center wards; 2. Schizophrenia patients meeting the diagnostic criteria of schizophrenia in the International Classification of Diseases (ICD-10); 3. 18 - 45 years old; 4. Good self-care ability; 5. Clinically stable (without acute exacerbation) for at least 1 week before enrollment, with a stable dose of antipsychotic drugs or other concomitant psychotropic drugs for at least 1 week; 6. No hand disabilities, and can use mobile phones or tablets normally; 7. Have a primary school education or above; 8. Normal vision and hearing, or within the normal range after correction; 9. Own and be able to independently use a smart phone or other electronic devices; 10. Patients and their families have given informed consent to this study, and voluntarily cooperate to participate in the intervention and sign the informed consent form. Exclusion Criteria: 1. not reside in Shanghai after discharge; 2. suffering from serious physical or brain organic diseases; 3. comorbid with other psychotic disorders.
Where this trial is running
Shanghai
- Shanghai Mental Health Center — Shanghai, China (Recruiting)
Study contacts
- Principal investigator: Jun Cai — Shanghai Mental Health Center
- Study coordinator: Weibo Zhang
- Email: zhangweibo600@163.com
- Phone: 86-13764694223
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.