MoodBrush app versus parent-modeled toothbrushing for children ages 3-6

Plaque Reduction: Digital vs. Parental Toothbrushing Instruction in Pediatric Patients

Not applicable Interventional University of Southern California · NCT07441148

This test will see if the MoodBrush app helps children ages 3-6 remove as much plaque as brushing modeled by a parent.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment112 (estimated)
Ages3 Years to 6 Years
SexAll
SponsorUniversity of Southern California Academic / other
Locations1 site (Los Angeles, California)
Trial IDNCT07441148 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial will enroll children aged 3-6 at the USC Advanced Pediatric Dental Clinic and AltaMed (Sunflower) clinic and randomly assign them to parent-modeled brushing or to use the MoodBrush digital app. Plaque will be measured on 12 tooth surfaces using the Silness and Loe Plaque Index immediately before and after a supervised two-minute brushing session. The primary outcome is the change in plaque index scores, with intrarater reliability checks and statistical analyses including paired t-tests within groups and two-sample t-tests between groups. The aim is to determine whether the app produces similar or greater plaque reduction compared with traditional parent-modeled instruction.

Who should consider this trial

Good fit: Children aged 3-6 years who are ASA I or II, speak English or Spanish, have cooperative behavior (Frankl 3 or 4), and are established patients at the participating clinics.

Not a fit: Children with extensive untreated caries, missing or unerupted teeth required for scoring, physical limitations preventing adequate brushing, or uncooperative behavior that prevents a full two-minute brushing session are unlikely to benefit.

Why it matters

Potential benefit: If successful, the free MoodBrush app could offer an engaging, scalable way to help young children brush more effectively and reduce plaque.

How similar studies have performed: Other pediatric studies of timer- and game-based brushing apps have improved brushing duration and engagement, but evidence that they consistently produce equal or better plaque reduction than parent-modeled brushing is limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA I or II
* children aged 3-6 years presenting for recall dental visit at AltaMed (Sunflower) clinic or USC Advanced Pediatric Dental Clinic
* must speak English or Spanish, Frankl 3 or 4.

Exclusion Criteria:

* Physical limitations that would prevent adequate oral hygiene
* Extensive caries preventing accurate readings on plaque index,
* Teeth needed for plaque score have not fully erupted or missing
* If behavior prevents them from cooperating for exam and toothbrushing
* Inability to brush for full two minutes.

Where this trial is running

Los Angeles, California

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Plaque Reductiontoothbrushingplaquedigital application
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.