Monitoring whooping cough in children in outpatient settings
National Surveillance of Pediatric Pertussis in Ambulatory Settings
This study looks at how well whooping cough vaccines protect children under 18 in France and tracks their health if they get sick with the disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 898 (estimated) |
| Ages | 1 Day to 18 Years |
| Sex | All |
| Sponsor | Association Clinique Thérapeutique Infantile du val de Marne Academic / other |
| Locations | 1 site (Créteil) |
| Trial ID | NCT04807712 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the surveillance of whooping cough (pertussis) in children under 18 years old in France, particularly those vaccinated with acellular vaccines. It aims to assess the duration of protection provided by these vaccines and to analyze clinical characteristics of vaccinated children. The study involves collecting data during initial visits when pertussis is suspected and during follow-up visits to monitor outcomes and laboratory results. It also includes training for laboratories on diagnostic procedures and monitoring infections caused by related bacteria.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 0-18 years with a suspected diagnosis of pertussis who require a biological examination.
Not a fit: Patients who are asymptomatic but have a confirmed family case of pertussis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of pertussis vaccine effectiveness and inform future vaccination strategies for children.
How similar studies have performed: Previous studies have shown success in monitoring vaccine effectiveness and disease characteristics, making this approach both relevant and valuable.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All children under 18 years old with a pertussis diagnosis is suspected and a biological exam is requested Exclusion Criteria: * children without symptoms with a household confirmed case * cases for which the pertussis diagnosis was not suspected by the pediatrician
Where this trial is running
Créteil
- Activ — Créteil, France (Recruiting)
Study contacts
- Study coordinator: Corinne Levy, MD
- Email: corinne.levy@activ-france.fr
- Phone: 0033148850404
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.