Monitoring the safety and effectiveness of peficitinib in rheumatoid arthritis patients in Japan

Japan Post-Marketing Surveillance - Specified Drug Use-results Survey for Peficitinib to Assess Safety and Effectiveness in the Patients With Rheumatoid Arthritis

Observational Astellas Pharma Inc · NCT03971253

This study is testing how safe and effective the medication peficitinib is for people with rheumatoid arthritis in Japan who are using it for the first time.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
SexAll
SponsorAstellas Pharma Inc Industry-sponsored
Drugs / interventionspeficitinib
Locations47 sites (Aichi and 46 other locations)
Trial IDNCT03971253 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the safety and effectiveness of peficitinib in patients with rheumatoid arthritis (RA) in a real-world clinical setting. It is a mandatory post-marketing surveillance requested by the Pharmaceuticals and Medical Devices Agency (PMDA) as part of Japan's Risk Management Plan. The study will include all patients who are treated with peficitinib for the first time, allowing for a comprehensive evaluation of its use in routine practice.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with rheumatoid arthritis who are starting treatment with peficitinib.

Not a fit: Patients who are not being treated with peficitinib will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the real-world effectiveness and safety profile of peficitinib for RA patients.

How similar studies have performed: Other post-marketing surveillance studies have shown success in evaluating the safety and effectiveness of treatments in real-world settings, making this approach well-established.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients with rheumatoid arthritis (RA) treated with peficitinib for the first time.

Exclusion Criteria:

* Not applicable.

Where this trial is running

Aichi and 46 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Rheumatoid ArthritisPost-Marketing SurveillanceASP015KSmyrafRheumatoid arthritisPeficitinib
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.