Monitoring patients with precancerous stomach lesions
Surveillance Strategies of Patients With Precancerous Conditions and Lesions in the Stomach
University of Latvia · NCT03250091
This study is trying to find out how to better monitor people with precancerous stomach lesions to see who is at risk of developing gastric cancer and when they should come back for check-ups.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Latvia (other) |
| Locations | 1 site (Riga) |
| Trial ID | NCT03250091 on ClinicalTrials.gov |
What this trial studies
This project focuses on identifying patients with precancerous lesions in the stomach to determine their risk of progressing to gastric cancer. It aims to stratify patients based on their risk levels and establish appropriate follow-up intervals for those at high risk. By implementing targeted endoscopic surveillance, the study seeks to improve early detection and management of gastric cancer, particularly in Latvia, where the incidence is high and late-stage diagnosis is common. The methodology includes upper endoscopy, biopsies, and sampling of plasma, serum, and fecal matter.
Who should consider this trial
Good fit: Ideal candidates are patients undergoing upper endoscopy who are motivated to participate and can provide signed consent.
Not a fit: Patients with known gastric cancer or those unwilling or unable to cooperate will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection and better management of gastric cancer, potentially reducing mortality rates.
How similar studies have performed: Other studies have shown success with targeted surveillance strategies for gastric cancer, making this approach promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients undergoing upper endoscopy Motivation to participate in the study Signed consent Exclusion Criteria: Known gastric cancer Unwillingness or inability to co-operate
Where this trial is running
Riga
- University of Latvia — Riga, Latvia (RECRUITING)
Study contacts
- Study coordinator: Ilze Kikuste, PhD
- Email: ikikuste@gmail.com
- Phone: 28357349
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gastric Cancer, Gastric Intestinal Metaplasia, Gastric Atrophy, Gastric Dysplasia, gastric precancerous lesions, gastric cancer, gastric intestinal Metaplasia, gastric atrophy