Monitoring patients with medication-related jaw issues

Identification of Therapeutic Exposures and Risk Factors Associated With Medication-Related Osteonecrosis of the Jaw

Observational Marmara University · NCT06430762

This study is looking at how patients with medication-related jaw issues recover over time to see what helps improve their treatment and quality of life.

Quick facts

Study typeObservational
Enrollment250 (estimated)
Ages18 Years to 110 Years
SexAll
SponsorMarmara University Academic / other
Locations1 site (Istanbul)
Trial IDNCT06430762 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients diagnosed with medication-related osteonecrosis of the jaw (MRONJ). Researchers will monitor these patients over time to understand their diagnosis, treatment, and follow-up processes. The study aims to identify how various factors, including patient background and health conditions, may affect recovery and quality of life. By gathering this data, the study seeks to improve understanding and management of MRONJ.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 18 and over who have been diagnosed with MRONJ and are seeking treatment at Marmara University Faculty of Dentistry.

Not a fit: Patients with non-drug-related osteonecrosis or those under 18 years old may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better management strategies and improved outcomes for patients suffering from MRONJ.

How similar studies have performed: While there may be limited studies specifically on MRONJ, similar observational approaches in other conditions have shown promise in understanding patient outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals aged 18 and over
* Male or female individuals
* Individuals who apply to the Marmara University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery due to medication-related osteonecrosis of jaw during the study period
* Individuals or their legal representatives who have given written consent to participate in the study

Exclusion Criteria:

* Non-drug-related osteonecrosis/osteomyelitis
* Osteoradionecrosis
* Metastasis to the oral region
* Individuals who have not given written consent to participate in the study
* Individuals under the age of 18

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Medication-Related Osteonecrosis of Jaw
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.