Clinical trial Recruiting at 1 site Observational Ages 18 to 110

Monitoring patients with medication-related jaw issues

Official title: Identification of Therapeutic Exposures and Risk Factors Associated With Medication-Related Osteonecrosis of the Jaw

Run by Marmara University · NCT06430762 · Data updated 2026-11-12

This study is looking at how patients with medication-related jaw issues recover over time to see what helps improve their treatment and quality of life.

Quick facts

Study typeObservational
Ages18 Years to 110 Years
SexAll
Enrollment250 (estimated)
SponsorMarmara University
Academic / other
Locations1 site (Istanbul)
StatusRecruiting
StartedApril 25, 2024
Main results expectedApril 25, 2026
Study endsApril 26, 2027
Registry record updatedMay 28, 2024
Trial IDNCT06430762 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals aged 18 and over who have been diagnosed with MRONJ and are seeking treatment at Marmara University Faculty of Dentistry.

Probably not a fit

Patients with non-drug-related osteonecrosis or those under 18 years old may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with medication-related osteonecrosis of the jaw (MRONJ). Researchers will monitor these patients over time to understand their diagnosis, treatment, and follow-up processes. The study aims to identify how various factors, including patient background and health conditions, may affect recovery and quality of life. By gathering this data, the study seeks to improve understanding and management of MRONJ.

Why it matters

Potential benefit: If successful, this study could lead to better management strategies and improved outcomes for patients suffering from MRONJ.

How similar studies have gone: While there may be limited studies specifically on MRONJ, similar observational approaches in other conditions have shown promise in understanding patient outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals aged 18 and over
* Male or female individuals
* Individuals who apply to the Marmara University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery due to medication-related osteonecrosis of jaw during the study period
* Individuals or their legal representatives who have given written consent to participate in the study

Exclusion Criteria:

* Non-drug-related osteonecrosis/osteomyelitis
* Osteoradionecrosis
* Metastasis to the oral region
* Individuals who have not given written consent to participate in the study
* Individuals under the age of 18

Where it's running

  • Marmara University School of Dentistry
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.