Monitoring pain levels during major abdominal surgery to improve patient care

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of using the Nociception Level Index (NOL) to guide pain management during major abdominal surgeries. It aims to determine how NOL monitoring can influence the administration of intravenous lidocaine and reduce opioid requirements for patients. The study will assess the impact of this multimodal analgesic approach on postoperative outcomes within the first 24 hours after surgery. By comparing traditional pain management techniques with NOL-guided strategies, the trial seeks to enhance patient recovery and comfort.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age \> 18 years
* ASA score I-III
* surgery for gastric or hepatobiliary or pancreatic neoplasia

Exclusion Criteria:

* pregnancy
* lactation
* neuraxial or regional anesthesia
* chronic treatment with drugs that can influence autonomic nervous system
* diuretics or nitroglycerin administration on the day of surgery
* severe neurological disability
* severe hemodynamic instability
* chronic pain
* chronic opioid treatment
* allergy to any of the study drugs
* severe untreated disease or organ failure
* pacemaker
* emergency surgery
* patient refusal to participate

Where it's running

• Regional Gastroenterology and Hepatology Institute Octavian Fodor
  Cluj-Napoca, Cluj, Romania Recruiting

Study contacts

• Study coordinator: Cristiana Osoian
• Email: osoiancris@yahoo.com
• Phone: +40743352189

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Energy needs after head and neck cancer surgery with free flap reconstruction

  This study tests how many calories people need before and after free flap surgery for head and neck cancer and whether nutrition relates to recovery and complications.

  Recruiting Tel-Aviv Sourasky Medical Center · Tel Aviv · NCT07759193

• A new treatment model for elderly lung cancer patients

  This trial tests a comprehensive, integrated care approach for older adults with lung cancer to improve perioperative management and outcomes.

  Recruiting Peking University People's Hospital · Beijing, Beijing Municipality · NCT07632664

• Guiding anesthesia with CoreSys during open abdominal hysterectomy

  This trial will test whether using CoreSys monitoring to guide anesthesia in women having elective open abdominal hysterectomy reduces inflammatory and hormonal stress responses after surgery.

  Recruiting Hospital Provincial de Rosario · Rosario, Santa Fe Province · NCT07571473

• Surgical techniques and outcomes across the lifespan in congenital heart disease in China

  See which surgical factors and care patterns affect recovery after heart surgery for people with complex congenital heart disease in China.

  Recruiting China National Center for Cardiovascular Diseases · Beijing · NCT07524998

• Giving Children a Voice in Pediatric Anesthesia

  This project tests whether asking children, parents, and clinicians about priorities can shape future pediatric anesthesia research in Switzerland.

  Recruiting at 7 sites Insel Gruppe AG, University Hospital Bern · Aarau, Canton of Aargau and 6 other locations · NCT07524049

• Comparing CCI and POSSUM to predict complications after gynecologic cancer surgery

  This project will test whether the Charlson Comorbidity Index (CCI) or the POSSUM score better predicts perioperative complications in adults having elective gynecologic cancer surgery.

  Recruiting Mahidol University · Bangkok · NCT07287280

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.