Monitoring health effects of workers exposed to micro and nanoplastics
Biomonitoring of Occupationally Populations Exposed to Micro and Nanoplastic
Universitat Autonoma de Barcelona · NCT06323603
This study is testing how exposure to tiny plastic particles affects the health of workers in industries that handle plastics.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 45 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Universitat Autonoma de Barcelona (other) |
| Locations | 4 sites (Helsinki and 3 other locations) |
| Trial ID | NCT06323603 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the health impacts of micro and nanoplastic exposure among workers in various industries, particularly those handling plastics. It aims to assess genotoxic damage and other health parameters by analyzing biological samples such as blood, urine, and feces. The study seeks to fill the knowledge gap regarding the health risks associated with micro and nanoplastics, which are increasingly prevalent due to plastic waste degradation. Participants must have been employed in their respective companies for at least 48 months and be in good health.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults over 18 years old who have been employed in industries dealing with plastics for at least four years.
Not a fit: Patients who may not benefit from this study include those with active or chronic diseases or those who have recently undergone X-ray examinations.
Why it matters
Potential benefit: If successful, this study could provide critical insights into the health risks associated with micro and nanoplastic exposure, potentially leading to improved safety regulations for workers.
How similar studies have performed: While there is limited data on the health effects of micro and nanoplastics, this study represents a novel approach to understanding their impact on occupational health.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged over 18 years. * Healthy subjects defined by the absence of evidence of any active or chronic disease following a detailed medical and surgical history, a complete physical examination including vital signs, 12-lead ECG, haematology, blood chemistry, and urine analysis. * Able to participate and willing to give written informed consent and to comply with the study restrictions. * Have been working at the company for the last 48 months Exclusion Criteria: * Workers decline participation * Legal incapacity or inability to understand or comply with the requirements of the study. * Any hierarchical subordination to the PI * Clinically significant findings as determined by medical history taking, physical examination, ECG, and vital signs. * Submitted to X-ray in the three previous months
Where this trial is running
Helsinki and 3 other locations
- Textile industry — Helsinki, Finland (COMPLETED)
- Recycling company — Alicante, Spain (COMPLETED)
- Textile Industry — Alicante, Spain (COMPLETED)
- Control recruitment — Barcelona, Spain (RECRUITING)
Study contacts
- Principal investigator: Julia Catalan, Researcher — FIOH
- Study coordinator: Alba Hernández, Professor
- Email: alba.hernandez@uab.cat
- Phone: +34 93 581 4702
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Occupational Exposure, Genotoxicity, Damage Dna, Biomonitoring, Genotoxic damage, Micro and nanoplastic