Monitoring fluid management in patients undergoing noncardiac surgery
Evaluation of the ZYNEX Cardiac Monitor in Patients Having Noncardiac Surgery
The Cleveland Clinic · NCT05536258
This study tests if using a special heart monitor to guide fluid management during major surgeries can help patients do better compared to standard methods.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 21 Years to 85 Years |
| Sex | All |
| Sponsor | The Cleveland Clinic (other) |
| Locations | 1 site (Cleveland, Ohio) |
| Trial ID | NCT05536258 on ClinicalTrials.gov |
What this trial studies
This observational trial evaluates the effectiveness of a cardiac monitor in guiding fluid administration during major noncardiac surgeries. Patients will be randomized into two groups: one receiving routine fluid management based on clinical judgment, and the other receiving fluid guidance based on real-time monitoring. The study aims to assess whether real-time monitoring can improve fluid management and patient outcomes during surgery. Anesthesia will be maintained throughout the procedure, and various parameters will be monitored to ensure patient safety.
Who should consider this trial
Good fit: Ideal candidates are adults aged 21-85 scheduled for major noncardiac surgery lasting at least two hours.
Not a fit: Patients with significant cardiac issues or severe obesity may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved fluid management and better surgical outcomes for patients undergoing noncardiac surgery.
How similar studies have performed: Other studies have shown promise in using real-time monitoring for fluid management, suggesting potential benefits in similar approaches.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adults having major non-cardiac surgery expected to last ≥2 hours 2. American Society of Anesthesiologists physical status 1-3 3. Age 21-85 years old 4. Planned endotracheal intubation and general anesthesia with or without any regional blocks. Exclusion Criteria: 1. Non-sinus heart rhythm; 2. amputation of any extremity; 3. eGFR \< 30 including end-stage kidney disease; 4. cardiac ejection fraction \< 50; 5. temporary or permanent pacemaker; 6. BMI \> 40 kg/m2. -
Where this trial is running
Cleveland, Ohio
- Cleveland Clinic — Cleveland, Ohio, United States (RECRUITING)
Study contacts
- Principal investigator: Kurt Ruetzler, MD — The Cleveland Clinic
- Study coordinator: Roberta Johnson
- Email: johnsor13@ccf.org
- Phone: 216-444-9950
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Noncardiac Surgery