Monitoring COVID-19 patients in Luxembourg to predict disease severity

Luxembourg Cohort of Positive Patients for COVID-19: a Stratification Study to Predict Patient Prognosis

Luxembourg Institute of Health · NCT04380987

This study is tracking COVID-19 patients in Luxembourg for two weeks to see what factors might lead to more severe illness compared to those with milder symptoms.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorLuxembourg Institute of Health (other gov)
Locations1 site (Luxembourg)
Trial IDNCT04380987 on ClinicalTrials.gov

What this trial studies

This observational study follows COVID-19 positive patients in Luxembourg for 14 days post-diagnosis, monitoring their health and symptoms digitally. Participants will complete daily questionnaires, and biological samples will be collected to analyze factors associated with disease severity. The study aims to identify risk factors for severe COVID-19 by comparing symptomatic patients with severe disease to those with mild cases managed at home. Follow-up evaluations will occur at weeks 3 and 4, and monthly for up to 12 months to assess long-term consequences.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have tested positive for COVID-19.

Not a fit: Patients who do not understand French or German or are already participating in another interventional COVID-19 study may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve understanding of COVID-19 severity factors, leading to better patient management and outcomes.

How similar studies have performed: Other studies have successfully utilized similar observational approaches to understand COVID-19, making this study a valuable addition to existing research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* SARS-CoV-2 infection as determined by PCR, performed by one of the certified laboratories in Luxembourg
* Signed informed consent form
* Age ≥18 years old
* Hospitalized or at home

Exclusion Criteria:

* Patients not understanding French or German
* Patients already included in an interventional study on Covid-19 (Discovery or other)

Where this trial is running

Luxembourg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Covid19, Severity factors, Patient stratification, Digital

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.