Monitoring brain function during carotid artery surgery

Correlation Between New O3 Regional Oximetry, Electroencephalography and the Somatosensory Evoked Potential in Carotid Endarterectomy Surgery

Observational Cleveland Clinic Abu Dhabi · NCT05267782

This study is testing new ways to monitor brain function during carotid artery surgery to see if it can help improve patient safety and outcomes.

Quick facts

Study typeObservational
Enrollment10 (estimated)
Ages18 Years and up
SexAll
SponsorCleveland Clinic Abu Dhabi Academic / other
Locations1 site (Abu Dhabi)
Trial IDNCT05267782 on ClinicalTrials.gov

What this trial studies

This observational study investigates the correlation between new O3 regional oximetry, electroencephalography (EEG), and somatosensory evoked potentials (SSEP) in patients undergoing carotid endarterectomy (CEA). The aim is to enhance the monitoring of cerebral ischemia during surgery, potentially improving patient outcomes by utilizing a multimodal approach to intraoperative monitoring. The study will involve patients over 18 years old who are classified as ASA I to III and are scheduled for CEA at Cleveland Clinic Abu Dhabi.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old scheduled for carotid endarterectomy with an ASA classification of I to III.

Not a fit: Patients with ASA classification IV and V, those with skin abnormalities affecting sensor placement, or those who are cognitively impaired may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved monitoring techniques that reduce the risk of stroke during carotid endarterectomy surgeries.

How similar studies have performed: Previous studies have indicated that multimodal monitoring techniques, including EEG and SSEP, can enhance diagnostic accuracy during similar surgical procedures.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Subjects older than 18 years of age
2. Subjects undergoing carotid endarterectomy.
3. American Society of Anaesthesiologists Classification (ASA) score I to III.

Exclusion Criteria:

1. American Society of Anaesthesiologists Classification (ASA) score IV and V.
2. Subject has skin abnormalities affecting the sensor placement
3. Emergency cases
4. Cognitive/Mentally impaired or unable to provide consent
5. Pregnant subject

Where this trial is running

Abu Dhabi

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Carotid EndarterectomyO3 regional oximetrysomatosensory evoked potentialelectroencephalographycarotid endarterectomy surgery
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.