Monitoring brain activity to assess pain during anesthesia
Acute Pain Oscillation in Electroencephalographic Monitoring Under General Anaesthesia: Characterisation of EEG Patterns Secondary to Pain
Hospital General Universitario de Valencia · NCT05873894
This study is testing how brain activity changes during surgery to see if it can help doctors understand and manage pain better for patients under anesthesia.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospital General Universitario de Valencia (other) |
| Locations | 2 sites (Valencia and 1 other locations) |
| Trial ID | NCT05873894 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate brain oscillatory activity in patients undergoing neurosurgery under general anesthesia to better understand acute pain responses. By using electroencephalography (EEG), the study will compare brain activity in four scenarios: awake with no pain, awake with pain, asleep with no pain, and asleep with pain. The goal is to establish a baseline of neural oscillations that can help detect unnoticed pain during surgery and improve postoperative pain management. Participants will be monitored during their procedure and followed up with a telephone survey regarding their pain levels three months and one year post-surgery.
Who should consider this trial
Good fit: Ideal candidates are adult patients scheduled for elective neurosurgery who are classified as ASA physical status I-IV.
Not a fit: Patients who are pregnant, have obstructive hydrocephaly, possess a neurostimulator, or require emergency surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved methods for detecting and managing pain in patients undergoing surgery, enhancing their overall recovery experience.
How similar studies have performed: While there is ongoing research into pain assessment using EEG, this specific approach to monitoring brain activity during anesthesia is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients that undergo schedule neurosurgery with neurophysiological monitorisation. * American Society of Anaesthesiologist physical status (ASA) I-IV. Exclusion Criteria: * Pregnancy * Obstructive hydrocephaly with or with a derivative catheter. * Patients with neurostimulator * Emergency surgery.
Where this trial is running
Valencia and 1 other locations
- CHGUV — Valencia, Spain (RECRUITING)
- CHGUV — Valencia, Spain (RECRUITING)
Study contacts
- Study coordinator: Carolina S Romero, PhD
- Email: romero_carolinasol@gva.es
- Phone: +34963187554
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pain