Monitoring anesthesia depth using EEG to improve recovery and cognition
EEG-based Depth of Anesthesia-monitoring During General Anesthesia - Effects on Time to Wake-up and Post-operative Cognition
This study tests if using brain wave monitoring during surgery can help doctors give the right amount of anesthesia to improve recovery and thinking skills afterward.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | Oslo University Hospital Academic / other |
| Locations | 1 site (Oslo) |
| Trial ID | NCT04529304 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of EEG-based monitoring to assess the depth of anesthesia during surgery. By analyzing raw EEG waveforms alongside established indexes, the researchers aim to tailor anesthetic dosages more effectively, potentially reducing the total amount of anesthetic used. The study also evaluates the impact of this individualized approach on postoperative cognitive function using standardized cognitive assessments. The goal is to minimize complications related to anesthesia, such as delayed recovery and cognitive dysfunction.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over the age of 18 who are undergoing surgical procedures requiring anesthesia.
Not a fit: Patients with psychiatric disorders, pregnancy, breastfeeding, or those on antiepileptic drugs may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to faster recovery times and improved cognitive outcomes for patients after surgery.
How similar studies have performed: Previous studies have shown promising results in using EEG for anesthesia monitoring, but this specific approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria . Participants are eligible to be included in the study only if all of the following criteria apply: Age 1. Participant must be above the age of 18 years , at the time of signing the informed consent. Sex 2. Male and/or female Informed Consent 3. Capable of giving signed informed consent as described in protocol which includes compliance with the requirements and restrictions listed in the informed consent form (ICF) and in the protocol Exclusion Criteria Participants are excluded from the study if any of the following criteria apply: 4. Psychiatric disorders 5. Pregnancy 6. Breast feeding 7. Using antiepileptic drugs. 8. Central neurological disease 9. Unable to complete baseline CANTAB-test.
Where this trial is running
Oslo
- Oslo University Hospital — Oslo, Norway (Recruiting)
Study contacts
- Principal investigator: Luis G Romundstad, MD, PhD — Oslo University Hospital
- Study coordinator: Anders Aasheim, Master
- Email: uxanim@ous-hf.no
- Phone: +4748129280
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.