Monitoring anal health in women with a history of high-grade HPV lesions
Official title: Anal Follow-up of Patients With a Gynecological History of High-grade Lesion and More Induced HPV
Run by Fondation Hôpital Saint-Joseph · NCT05566106 · Data updated 2026-11-12
This study is trying to see if regular check-ups can help women with a history of high-grade HPV lesions catch any signs of anal cancer early.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 1500 (estimated) |
| Sponsor | Fondation Hôpital Saint-Joseph Academic / other |
| Locations | 1 site (Paris) |
| Status | Recruiting |
| Started | September 22, 2022 |
| Main results expected | August 1, 2032 |
| Study ends | December 31, 2032 |
| Registry record updated | October 6, 2022 |
| Trial ID | NCT05566106 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women aged 18 and older with a history of high-grade HPV-induced gynecological lesions who are participating in proctology follow-up.
✕Probably not a fit
Patients with a history of induced high-grade anal HPV lesions or those under legal guardianship may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on women aged 18 and older who have a history of high-grade HPV-induced gynecological lesions. It aims to monitor these patients through a proctology follow-up protocol to assess the potential development of anal cancer, which is significantly linked to HPV. The study seeks to gather data on the incidence of anal lesions and improve early diagnosis, thereby potentially reducing the risk of anal cancer. Participants must be French-speaking and consent to the use of their data for research purposes.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and prevention strategies for anal cancer in women with a history of HPV-related lesions.
How similar studies have gone: While there is limited data on similar studies, the focus on early diagnosis of anal lesions in HPV-infected populations is a relatively novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient whose age ≥ 18 years * Patient with a high-grade or higher HPV-induced gynecological lesion * Patient participating in the proctology follow-up protocol * French-speaking patient Exclusion Criteria: * Patient with a history of induced high-grade anal HPV lesion and above * Patient under guardianship or curatorship * Patient deprived of liberty * Patient under court protection * Patient objecting to the use of his/her data for this research
Where it's running
-
Groupe Hospitalier Paris Saint-Joseph
Paris, France Recruiting
Study contacts
- Principal investigator: Sophie Wylomanski, MD — Fondation Hôpital Saint-Joseph
- Study coordinator: Sophie Wylomanski, MD
- Email: swylomanski@ghpsj.fr
- Phone: 144127173
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.