Mollii neuromodulation suit to improve function and quality of life after stroke or multiple sclerosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with either a first ischemic stroke or confirmed multiple sclerosis will wear the Mollii garment with active electrical stimulation or a visually identical garment with the stimulation turned off (placebo). Objective measures of mobility, gait, balance, and clinical symptoms will be collected alongside patient-reported quality of life questionnaires, and participants will be followed over time to track changes. The protocol compares outcomes between the stroke and MS groups and examines the relationship between subjective reports and objective measures to map any placebo effect. Safety, tolerability, and subgroup differences will also be recorded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* suffered a first ischemic stroke, diagnosed by a neurologist based on CT or MR imaging
* neurological examination revealed mobility and postural limitations
* confirmed multiple sclerosis diagnosed by a neurologist based on MRI imaging

Exclusion Criteria:

* multiple strokes in medical history
* systolic blood pressure less than 120 or higher than 160 mmHg
* orthostatic hypotension
* arotid artery stenosis
* severe heart disease
* hemophilia
* traumatic brain injury
* seizure disorder
* untreated diabetes
* abnormal electroencephalography
* abnormal blood panel
* use of sedatives
* irregular medication use
* severe aphasia (Western Aphasia Battery ≤ 25)
* severe visual or hearing impairment
* severe sensory dysfunction
* severe orthopedic problems
* other neurological conditions affecting motor function
* alcoholism
* drug use
* smoking after diagnosis of stroke
* unable to walk at least 10 m with or without assistance in 6 minutes
* BBS score ≤ 32
* BI score ≤ 70
* current participation in individual or group exercise program outside of standard physical therapy

Where it's running

• Somogy County Kaposi Mór Teaching Hospital
  Kaposvár, Somogy County, Hungary Recruiting

Study contacts

• Principal investigator: József Dr. habil Tollár — Somogy County Kaposi Mór Teaching Hospital
• Study coordinator: Barbara Kopácsi
• Email: kbarbi0108@gmail.com
• Phone: +36308340545

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.