Molecular classification of endometrial cancer in Mexican patients
Official title: Molecular Classification in Mexican Patients With Endometrial Cancer and Its Impact on Prognosis
Run by National Institute of Cancerología · NCT06206083 · Data updated 2026-11-12
This study is trying to see how the different types of endometrial cancer in Mexican women can help doctors predict outcomes and find better treatments.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 64 (estimated) |
| Sponsor | National Institute of Cancerología Government |
| Locations | 1 site (Mexico City, Mexico City) |
| Status | Recruiting |
| Started | March 1, 2024 |
| Main results expected | November 1, 2026 |
| Study ends | February 1, 2027 |
| Registry record updated | February 28, 2024 |
| Trial ID | NCT06206083 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women over 18 years old diagnosed with endometrioid-type endometrial cancer who have undergone surgery at the Instituto Nacional de Cancerología.
✕Probably not a fit
Patients with non-endometrioid type endometrial cancer or those with a history of malignancy within the last five years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to determine the molecular classification of endometrial cancer (EC) in Mexican women, focusing on the endometrioid subtype. By utilizing next-generation sequencing to detect specific mutations and immunohistochemical analysis for microsatellite instability, the study seeks to establish a more accurate prognosis for patients. The research will analyze samples collected from patients treated at the Instituto Nacional de Cancerología between 2015 and 2019, evaluating the impact of molecular classification on clinical outcomes and potential targeted therapies.
Why it matters
Potential benefit: If successful, this study could lead to more personalized treatment strategies and improved prognostic accuracy for patients with endometrial cancer.
How similar studies have gone: While this approach is novel in the context of Mexican patients, similar studies in other populations have shown promising results in using molecular classification for prognosis in endometrial cancer.
Who can join: the full rules
Show full inclusion / exclusion criteria
Criteria: Inclusion Criteria: * Clinical diagnosis of endometrioid-type endometrial cancer with samples available * That the patients have undergone surgery at INCan. Exclusion Criteria: * Samples with CEE of non-endometroid type. * Samples from patients with double primary neoplasm, including carcinoma ductal in situ, squamous cell skin cancers, and cervical carcinoma in situ * History of malignancy \< 5 years prior with no evidence of disease (i.e., remission).
Where it's running
-
Instituto Nacional de Cancerología
Mexico City, Mexico City, Mexico Recruiting
Study contacts
- Principal investigator: David F Cantu-de-León, PhD — The Principal Investigator
- Study coordinator: David F Cantu-de-León, PhD
- Email: dfcantu@gmail.com
- Phone: +52-55-5628-0400
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.